serw-MX  [xml]  

 DeCS Categories

D02 Organic Chemicals .
D02.241 Carboxylic Acids .
D02.241.081 Acids, Acyclic .
D02.241.081.337 Dicarboxylic Acids .
D02.241.081.337.351 Glutarates .
D02.241.081.337.351.550 Meglutol .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.047 Alcohol Oxidoreductases .
D08.811.682.047.820 NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases .
D08.811.682.047.820.150 3-Hydroxyacyl CoA Dehydrogenases .
D08.811.682.047.820.150.415 Hydroxymethylglutaryl CoA Reductases .
D08.811.682.047.820.150.415.250 Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent .
 Synonyms & Historicals
Hydroxymethylglutaryl CoA Reductases .
3-Hydroxy-3-methylglutaryl CoA Reductase .
HMG CoA Reductase .
Hydroxymethylglutaryl CoA Reductase .
3 Hydroxy 3 methylglutaryl CoA Reductase .
CoA Reductase, 3-Hydroxy-3-methylglutaryl .
Reductase, 3-Hydroxy-3-methylglutaryl CoA .
HMG CoA Reductases .
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID. .
Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent .
3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent .
HMG CoA Reductase, NAD-Dependent .
Hydroxymethylglutaryl CoA Reductase, NAD-Dependent .
CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl .
HMG CoA Reductase, NAD Dependent .
HMG CoA Reductases, NAD Dependent .
Hydroxymethylglutaryl CoA Reductase, NAD Dependent .
NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase .
NAD-Dependent Hydroxymethylglutaryl-CoA Reductases .
HMG CoA Reductases, NAD-Dependent .
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH. .
Meglutol .
3-Hydroxy-3-methylpentanedioic Acid .
beta-Hydroxy-beta-Methylglutarate .
3 Hydroxy 3 methylglutaric Acid .
3 Hydroxy 3 methylpentanedioic Acid .
Acid, 3-Hydroxy-3-methylglutaric .
Acid, 3-Hydroxy-3-methylpentanedioic .
beta Hydroxy beta Methylglutarate .
3-Hydroxy-3-methylglutaric Acid .
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol. .