serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.241 Carboxylic Acids .
D02.241.081 Acids, Acyclic .
D02.241.081.337 Dicarboxylic Acids .
D02.241.081.337.351 Glutarates .
D02.241.081.337.351.550 Meglutol .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.047 Alcohol Oxidoreductases .
D08.811.682.047.820 NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases .
D08.811.682.047.820.150 3-Hydroxyacyl CoA Dehydrogenases .
D08.811.682.047.820.150.415 Hydroxymethylglutaryl CoA Reductases .
D08.811.682.047.820.150.415.750 Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent .
D08.811.913 Transferases .
D08.811.913.050 Acyltransferases .
D08.811.913.050.612 Hydroxymethylglutaryl-CoA Synthase .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Hydroxymethylglutaryl-CoA Synthase .
3-hydroxy-3-methylglutaryl-coenzyme A synthase .
HMG-CoA synthase .
Hydroxymethylglutaryl CoA Synthase .
Synthase, Hydroxymethylglutaryl-CoA .
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5. .
1.00
 
Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent .
3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent .
HMG CoA-Reductases, NADP-Dependent .
Hydroxymethylglutaryl-Coenzyme A Reductase (NADP) .
3 Hydroxy 3 methylglutaryl coenzyme A reductase, NADP dependent .
CoA-Reductases, NADP-Dependent HMG .
HMG CoA Reductases, NADP Dependent .
NADP-Dependent HMG CoA-Reductases .
NADP-dependent Hydroxymethylglutaryl-CoA-Reductases .
Hydroxymethylglutaryl-CoA-Reductase (NADP) .
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis. .
0.72
 
Meglutol .
3-Hydroxy-3-methylpentanedioic Acid .
beta-Hydroxy-beta-Methylglutarate .
3 Hydroxy 3 methylglutaric Acid .
3 Hydroxy 3 methylpentanedioic Acid .
Acid, 3-Hydroxy-3-methylglutaric .
Acid, 3-Hydroxy-3-methylpentanedioic .
beta Hydroxy beta Methylglutarate .
3-Hydroxy-3-methylglutaric Acid .
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol. .
0.70
 
Hydroxymethylglutaryl CoA Reductases .
3-Hydroxy-3-methylglutaryl CoA Reductase .
HMG CoA Reductase .
Hydroxymethylglutaryl CoA Reductase .
3 Hydroxy 3 methylglutaryl CoA Reductase .
CoA Reductase, 3-Hydroxy-3-methylglutaryl .
Reductase, 3-Hydroxy-3-methylglutaryl CoA .
HMG CoA Reductases .
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID. .
0.69