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 DeCS Categories

D02 Organic Chemicals .
D02.092 Amines .
D02.092.211 Biogenic Amines .
D02.092.211.215 Biogenic Monoamines .
D02.092.211.215.811 Tyramine .
D02.455 Hydrocarbons .
D02.455.526 Hydrocarbons, Halogenated .
D02.455.526.728 Mustard Compounds .
D02.455.526.728.650 Nitrogen Mustard Compounds .
D02.455.526.728.650.050 Aniline Mustard .
D02.455.526.728.650.156 Chlorambucil .
D02.455.526.728.650.529 Mechlorethamine .
D02.455.526.728.650.594 Melphalan .
D02.455.526.728.650.913 Uracil Mustard .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.742 Pyrimidines .
D03.383.742.698 Pyrimidinones .
D03.383.742.698.875 Uracil .
D03.383.742.698.875.949 Uracil Mustard .
D12 Amino Acids, Peptides, and Proteins .
D12.125 Amino Acids .
D12.125.072 Amino Acids, Cyclic .
D12.125.072.050 Amino Acids, Aromatic .
D12.125.072.050.685 Phenylalanine .
D12.125.072.050.685.440 Fenclonine .
D12.125.072.050.685.500 Melphalan .
D12.125.142 Amino Acids, Essential .
D12.125.142.666 Phenylalanine .
 
 Terms
 Synonyms & Historicals		Documents
LILACS e MDL		 
Melphalan .
4-(Bis(2-chloroethyl)amino)phenylalanine .
Alkeran .
L-PAM .
Mustard, Phenylalanine .
Medphalan .
Merphalan .
Phenylalanine Mustard .
Sarcolysine .
Sarkolysin .
An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. .
1.00
256876
 
Mechlorethamine .
Bis(2-chloroethyl)methylamine .
Caryolysine .
Cloramin .
Embichin .
Mechlorethamine Hydrochloride .
Mechlorethamine Hydrochloride N-Oxide .
Mechlorethamine N-Oxide .
Methylchlorethamine .
Mitomen .
Mustargen .
NSC-10107 .
NSC-762 .
Nitrogranulogen .
Nitromin .
Hydrochloride N-Oxide, Mechlorethamine .
Hydrochloride, Mechlorethamine .
Mechlorethamine Hydrochloride N Oxide .
Mechlorethamine N Oxide .
N-Oxide, Mechlorethamine Hydrochloride .
N-Oxide, Nitrogen Mustard .
NSC 10107 .
NSC 762 .
NSC10107 .
NSC762 .
Nitrogen Mustard N Oxide .
Chlorethazine .
Chlormethine .
Mechlorethamine Oxide .
Mustine .
Nitrogen Mustard .
Nitrogen Mustard N-Oxide .
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. .
0.67
123102
 
Chlorambucil .
4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid .
Amboclorin .
CB-1348 .
Chloraminophene .
Chlorbutin .
Leukeran .
Lympholysin .
N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid .
NSC-3088 .
CB 1348 .
CB1348 .
NSC 3088 .
NSC3088 .
A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) .
0.66
353401
 
Tyramine .
4-(2-Aminoethyl)phenol .
4-Hydroxyphenethylamine .
p-Tyramine .
para-Tyramine .
4 Hydroxyphenethylamine .
An indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and MONOAMINE OXIDASE to prolong the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals and may be a neurotransmitter in some invertebrate nervous systems. .
0.60
104901
 
Aniline Mustard .
Lymphochin .
Lymphocin .
Lymphoquin .
N,N-Di(2-Chloroethyl)aniline .
N,N-bis(2-chloroethyl)aniline .
N,N-bis-(2-chloroethyl)aniline .
Mustard, Aniline .
Alkylating anti-neoplastic agent. .
0.56
587
 
Uracil Mustard .
5-(Bis(2-chloroethyl)amino)-2,4-(1H,3H)pyrimidinedione .
Mustard, Uracil .
Uramustine .
Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage. .
0.54
073
 
Phenylalanine .
Endorphenyl .
L-Phenylalanine .
Phenylalanine, L-Isomer .
L-Isomer Phenylalanine .
Phenylalanine, L Isomer .
An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE. .
0.51
6320095
 
Fenclonine .
CP-10,188 .
DL-3-(4-Chlorophenyl)alanine .
Fenclonin .
Fenclonine (L)-Isomer .
Fenclonine Hydrobromide .
Fenclonine Hydrochloride .
Fenclonine, (D)-Isomer .
Hydrobromide, Fenclonine .
Hydrochloride, Fenclonine .
para Chlorophenylalanine .
p-Chlorophenylalanine .
para-Chlorophenylalanine .
A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin. .
0.51
72564