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 DeCS Categories

D06 Hormones, Hormone Substitutes, and Hormone Antagonists .
D06.472 Hormones .
D06.472.699 Peptide Hormones .
D06.472.699.327 Hypothalamic Hormones .
D06.472.699.327.935 Pro-Opiomelanocortin .
D06.472.699.327.935.498 Corticotropin-Like Intermediate Lobe Peptide .
D06.472.699.584 Natriuretic Peptides .
D06.472.699.584.625 Natriuretic Peptide, Brain .
D06.472.699.584.750 Natriuretic Peptide, C-Type .
D06.472.699.592 Peptide PHI .
D06.472.699.631 Pituitary Hormones .
D06.472.699.631.525 Pituitary Hormones, Anterior .
D06.472.699.631.525.600 Pro-Opiomelanocortin .
D06.472.699.631.525.600.498 Corticotropin-Like Intermediate Lobe Peptide .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.352 Esterases .
D08.811.277.352.640 Phosphoric Diester Hydrolases .
D08.811.277.352.640.150 3',5'-Cyclic-AMP Phosphodiesterases .
D08.811.277.352.640.150.500 Cyclic Nucleotide Phosphodiesterases, Type 5 .
D08.811.277.352.640.155 3',5'-Cyclic-GMP Phosphodiesterases .
D08.811.277.352.640.155.500 Cyclic Nucleotide Phosphodiesterases, Type 5 .
D08.811.913 Transferases .
D08.811.913.696 Phosphotransferases .
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) .
D08.811.913.696.620.682 Protein Kinases .
D08.811.913.696.620.682.725 Protein-Tyrosine Kinases .
D08.811.913.696.620.682.725.400 Receptor Protein-Tyrosine Kinases .
D08.811.913.696.620.682.725.400.950 Receptors, Vascular Endothelial Growth Factor .
D10 Lipids .
D10.251 Fatty Acids .
D10.251.355 Fatty Acids, Unsaturated .
D10.251.355.255 Eicosanoids .
D10.251.355.255.100 Arachidonic Acids .
D10.251.355.255.100.450 Leukotrienes .
D10.251.355.255.100.450.855 SRS-A .
D10.251.355.255.100.450.855.455 Leukotriene C4 .
D10.251.355.310 Fatty Acids, Essential .
D10.251.355.310.166 Arachidonic Acids .
D10.251.355.310.166.887 Leukotrienes .
D10.251.355.310.166.887.855 SRS-A .
D10.251.355.310.166.887.855.455 Leukotriene C4 .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.276 Intercellular Signaling Peptides and Proteins .
D12.644.276.100 Angiogenic Proteins .
D12.644.276.100.800 Vascular Endothelial Growth Factors .
D12.644.276.100.800.200 Vascular Endothelial Growth Factor A .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.008 3',5'-Cyclic-AMP Phosphodiesterases .
D12.644.360.008.500 Cyclic Nucleotide Phosphodiesterases, Type 5 .
D12.644.360.009 3',5'-Cyclic-GMP Phosphodiesterases .
D12.644.360.009.500 Cyclic Nucleotide Phosphodiesterases, Type 5 .
D12.644.400 Neuropeptides .
D12.644.400.097 Calcitonin Gene-Related Peptide .
D12.644.400.400 Hypothalamic Hormones .
D12.644.400.400.935 Pro-Opiomelanocortin .
D12.644.400.400.935.498 Corticotropin-Like Intermediate Lobe Peptide .
D12.644.400.610 Peptide PHI .
D12.644.548 Peptide Hormones .
D12.644.548.365 Hypothalamic Hormones .
D12.644.548.365.935 Pro-Opiomelanocortin .
D12.644.548.365.935.498 Corticotropin-Like Intermediate Lobe Peptide .
D12.644.548.585 Natriuretic Peptides .
D12.644.548.585.625 Natriuretic Peptide, Brain .
D12.644.548.585.750 Natriuretic Peptide, C-Type .
D12.644.548.592 Peptide PHI .
D12.644.548.691 Pituitary Hormones .
D12.644.548.691.525 Pituitary Hormones, Anterior .
D12.644.548.691.525.690 Pro-Opiomelanocortin .
D12.644.548.691.525.690.498 Corticotropin-Like Intermediate Lobe Peptide .
D12.776 Proteins .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.100 Angiogenic Proteins .
D12.776.467.100.800 Vascular Endothelial Growth Factors .
D12.776.467.100.800.200 Vascular Endothelial Growth Factor A .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.008 3',5'-Cyclic-AMP Phosphodiesterases .
D12.776.476.008.500 Cyclic Nucleotide Phosphodiesterases, Type 5 .
D12.776.476.009 3',5'-Cyclic-GMP Phosphodiesterases .
D12.776.476.009.500 Cyclic Nucleotide Phosphodiesterases, Type 5 .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.630 Receptor Protein-Tyrosine Kinases .
D12.776.543.750.630.750 Receptors, Vascular Endothelial Growth Factor .
D12.776.543.750.750 Receptors, Peptide .
D12.776.543.750.750.400 Receptors, Growth Factor .
D12.776.543.750.750.400.910 Receptors, Vascular Endothelial Growth Factor .
D12.776.631 Nerve Tissue Proteins .
D12.776.631.590 Natriuretic Peptide, Brain .
D12.776.631.650 Neuropeptides .
D12.776.631.650.097 Calcitonin Gene-Related Peptide .
D12.776.631.650.405 Hypothalamic Hormones .
D12.776.631.650.405.935 Pro-Opiomelanocortin .
D12.776.631.650.405.935.498 Corticotropin-Like Intermediate Lobe Peptide .
D12.776.631.650.610 Peptide PHI .
D23 Biological Factors .
D23.469 Inflammation Mediators .
D23.469.050 Autacoids .
D23.469.050.175 Eicosanoids .
D23.469.050.175.450 Leukotrienes .
D23.469.050.175.450.725 SRS-A .
D23.469.050.175.450.725.400 Leukotriene C4 .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.100 Angiogenic Proteins .
D23.529.100.800 Vascular Endothelial Growth Factors .
D23.529.100.800.200 Vascular Endothelial Growth Factor A .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.954 Therapeutic Uses .
D27.505.954.411 Cardiovascular Agents .
D27.505.954.411.918 Vasodilator Agents .
D27.505.954.411.918.500 Endothelium-Dependent Relaxing Factors .
 Synonyms & Historicals
Natriuretic Peptide, C-Type .
C-Type Natriuretic Peptide-22 .
C-Type Natriuretic Peptide-53 .
CNP-22 .
CNP-53 .
C Type Natriuretic Peptide .
C Type Natriuretic Peptide 22 .
C Type Natriuretic Peptide 53 .
Natriuretic Peptide, C Type .
Natriuretic Peptide-22, C-Type .
Natriuretic Peptide-53, C-Type .
Peptide, C-Type Natriuretic .
Peptide-22, C-Type Natriuretic .
Peptide-53, C-Type Natriuretic .
C-Type Natriuretic Peptide .
A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified. .
Calcitonin Gene-Related Peptide .
Calcitonin Gene-Related Peptide I .
Calcitonin Gene-Related Peptide II .
alpha-CGRP .
beta-CGRP .
Calcitonin Gene Related Peptide .
Calcitonin Gene Related Peptide I .
Calcitonin Gene Related Peptide II .
Gene-Related Peptide, Calcitonin .
Peptide, Calcitonin Gene-Related .
alpha CGRP .
beta CGRP .
A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. .
Receptors, Vascular Endothelial Growth Factor .
Endothelial Growth Factor Receptor .
Receptor, Endothelial Growth Factors .
Receptor, Vascular Endothelial Cell Growth Factor .
Receptor, Vascular Permeability Factor .
VEGF Receptor .
VEGF Receptors .
VPF Receptor .
Vascular Endothelial Cell Growth Factor Receptor .
Vascular Endothelial Growth Factor Receptor .
Vascular Permeability Factor Receptor .
Receptors, VEGF .
A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels. .
Cyclic Nucleotide Phosphodiesterases, Type 5 .
PDE5 Phosphodiesterases .
Phosphodiesterase 5 .
Phosphodiesterase 5A .
Phosphodiesterase 5A, cGMP-Specific .
Phosphodiesterase Type 5 .
Phosphodiesterase Type V .
Phosphodiesterase V .
Phosphodiesterase-5 .
cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase .
Phosphodiesterase 5A, cGMP Specific .
Phosphodiesterases, PDE5 .
Type 5, Phosphodiesterase .
Type V, Phosphodiesterase .
cGMP-Specific Phosphodiesterase 5A .
A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction. .
Endothelium-Dependent Relaxing Factors .
Endothelium-Dependent Relaxing Factor .
Endothelium-Dependent Vasodilators .
Endothelium-Derived Relaxant Factor .
Neutrophil-Derived Relaxant Factor .
Endothelium Dependent Relaxing Factor .
Endothelium Dependent Relaxing Factors .
Endothelium Dependent Vasodilators .
Endothelium Derived Relaxant Factor .
Endothelium Derived Relaxing Factor .
Factor, Neutrophil-Derived Relaxant .
Neutrophil Derived Relaxant Factor .
Relaxant Factor, Endothelium-Derived .
Relaxant Factor, Neutrophil-Derived .
Relaxing Factor, Endothelium-Dependent .
Relaxing Factor, Endothelium-Derived .
Relaxing Factors, Endothelium-Dependent .
Vasodilators, Endothelium-Dependent .
Endothelium-Derived Relaxing Factor .
Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN. .
Corticotropin-Like Intermediate Lobe Peptide .
ACTH(18-39) .
ACTHalpha(18-39), Ser(31)- .
ACTHalpha(18-39), Serine(31)- .
CLIP (ACTH 18-39) .
Corticotropin Like Intermediate Lobe Peptide .
A peptide derived from the cleavage of ADRENOCORTICOTROPIC HORMONE, found primarily in the INTERMEDIATE LOBE OF PITUITARY but also in the ARCUATE NUCLEUS of basal HYPOTHALAMUS. Its sequence is identical to the C-terminal 22-amino acids of ACTH or ACTH 18-39. .
Peptide PHI .
Human PHI .
PHM Neuropeptide .
PHM-27 .
Peptide HI .
Peptide Histidine Methionine .
Peptide PHI-27 .
Peptide-Histidine-Isoleucinamide .
Porcine Intestinal Heptacosapeptide .
Pro-Vasoactive Intestinal Peptide .
Heptacosapeptide, Porcine Intestinal .
Histidine Methionine, Peptide .
Histidine-Isoleucine, Peptide .
Intestinal Heptacosapeptide, Porcine .
Intestinal Peptide, Pro-Vasoactive .
Methionine, Peptide Histidine .
Neuropeptide, PHM .
PHI, Human .
PHM, Peptide .
Peptide Histidine Isoleucinamide .
Peptide Histidine Isoleucine .
Peptide PHI 27 .
Peptide, PHI .
Peptide, Pro-Vasoactive Intestinal .
Pro Vasoactive Intestinal Peptide .
Neuropeptide PHI 27 .
Peptide Histidine-Isoleucine .
Peptide PHM .
PHI Peptide .
A 27-amino acid peptide with histidine at the N-terminal and isoleucine amide at the C-terminal. The exact amino acid composition of the peptide is species dependent. The peptide is secreted in the intestine, but is found in the nervous system, many organs, and in the majority of peripheral tissues. It has a wide range of biological actions, affecting the cardiovascular, gastrointestinal, respiratory, and central nervous systems. .
Vascular Endothelial Growth Factor A .
Glioma-Derived Vascular Endothelial Cell Growth Factor .
VEGF 25902 .
Vascular Permeability Factor .
Vasculotropin .
Glioma Derived Vascular Endothelial Cell Growth Factor .
Permeability Factor, Vascular .
Vascular Endothelial Growth Factor .
Vascular Endothelial Growth Factor-A .
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced. .
Natriuretic Peptide, Brain .
B-Type Natriuretic Peptide .
BNP Gene Product .
BNP-32 .
Brain Natriuretic Peptide-32 .
Natrecor .
Natriuretic Factor-32 .
Natriuretic Peptide Type-B .
Type-B Natriuretic Peptide .
Ventricular Natriuretic Peptide, B-type .
BNP 32 .
Brain Natriuretic Peptide 32 .
Natriuretic Factor 32 .
Natriuretic Peptide Type B .
Natriuretic Peptide, B-Type .
Natriuretic Peptide, Type-B .
Natriuretic Peptide-32, Brain .
Peptide, Brain Natriuretic .
Peptide-32, Brain Natriuretic .
Type B Natriuretic Peptide .
Ventricular Natriuretic Peptide, B type .
Brain Natriuretic Peptide .
Nesiritide .
A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS. .
Leukotriene C4 .
Leukotriene C .
Leukotriene C-1 .
Leukotriene C-4 .
Leukotriene C1 .
Leukotrienes C .
Leukotriene C 1 .
Leukotriene C 4 .
LTC4 19440 .
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990) .