serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.392 Hydrocarbons, Alicyclic .
D02.455.426.392.368 Cycloparaffins .
D02.455.426.392.368.367 Cyclohexanes .
D02.455.426.392.368.367.800 Picrotoxin .
D02.540 Lactones .
D02.540.552 Picrotoxin .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.742 Pyrimidines .
D03.383.742.698 Pyrimidinones .
D03.383.742.698.253 Barbiturates .
D03.383.742.698.253.650 Phenobarbital .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.530 Membrane Transport Proteins .
D12.776.157.530.400 Ion Channels .
D12.776.157.530.400.175 Chloride Channels .
D12.776.157.530.400.175.562 Receptors, GABA-A .
D12.776.157.530.400.400 Ligand-Gated Ion Channels .
D12.776.157.530.400.400.100 Cysteine Loop Ligand-Gated Ion Channel Receptors .
D12.776.157.530.400.400.100.100 Receptors, GABA-A .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.450 Ion Channels .
D12.776.543.550.450.175 Chloride Channels .
D12.776.543.550.450.175.562 Receptors, GABA-A .
D12.776.543.550.450.500 Ligand-Gated Ion Channels .
D12.776.543.550.450.500.100 Cysteine Loop Ligand-Gated Ion Channel Receptors .
D12.776.543.550.450.500.100.100 Receptors, GABA-A .
D12.776.543.585 Membrane Transport Proteins .
D12.776.543.585.400 Ion Channels .
D12.776.543.585.400.175 Chloride Channels .
D12.776.543.585.400.175.562 Receptors, GABA-A .
D12.776.543.585.400.500 Ligand-Gated Ion Channels .
D12.776.543.585.400.500.100 Cysteine Loop Ligand-Gated Ion Channel Receptors .
D12.776.543.585.400.500.100.100 Receptors, GABA-A .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.130 Cysteine Loop Ligand-Gated Ion Channel Receptors .
D12.776.543.750.130.500 Receptors, GABA-A .
D12.776.543.750.720 Receptors, Neurotransmitter .
D12.776.543.750.720.200 Receptors, Amino Acid .
D12.776.543.750.720.200.300 Receptors, GABA .
D12.776.543.750.720.200.300.300 Receptors, GABA-A .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Phenobarbital .
Gardenal .
Hysteps .
Luminal .
Phenobarbital Sodium .
Phenobarbital, Monosodium Salt .
Phenylethylbarbituric Acid .
Acid, Phenylethylbarbituric .
Monosodium Salt Phenobarbital .
Sodium, Phenobarbital .
Phenemal .
Phenobarbitone .
Phenylbarbital .
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. .
1.00
17616651
 
Receptors, Amino Acid .
Receptor, Amino Acid .
Receptors, Amino Acids .
Amino Acid Receptor .
Amino Acids Receptors .
Amino Acid Receptors .
Cell surface proteins that bind amino acids and trigger changes which influence the behavior of cells. Glutamate receptors are the most common receptors for fast excitatory synaptic transmission in the vertebrate central nervous system, and GAMMA-AMINOBUTYRIC ACID and glycine receptors are the most common receptors for fast inhibition. .
0.41
2972
 
Picrotoxin .
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. .
0.40
163871
 
Receptors, GABA .
GABA Receptor .
gamma-Aminobutyric Acid Receptor .
Receptor, GABA .
Receptor, gamma-Aminobutyric Acid .
Receptors, gamma Aminobutyric Acid .
gamma Aminobutyric Acid Receptor .
gamma Aminobutyric Acid Receptors .
gamma-Aminobutyric Acid Receptors .
GABA Receptors .
Receptors, gamma-Aminobutyric Acid .
Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen. .
0.40
233484
 
Receptors, GABA-A .
Benzodiazepine Receptor .
Benzodiazepine Receptors .
Benzodiazepine-GABA Receptor .
Diazepam Receptor .
Diazepam Receptors .
GABA(A) Receptor .
GABA-A Receptor .
GABA-A Receptor alpha Subunit .
GABA-A Receptor beta Subunit .
GABA-A Receptor delta Subunit .
GABA-A Receptor epsilon Subunit .
GABA-A Receptor gamma Subunit .
GABA-A Receptor rho Subunit .
GABA-Benzodiazepine Receptor .
GABA-Benzodiazepine Receptors .
Muscimol Receptor .
Muscimol Receptors .
delta Subunit, GABA-A Receptor .
epsilon Subunit, GABA-A Receptor .
gamma-Aminobutyric Acid Subtype A Receptors .
Benzodiazepine GABA Receptor .
Benzodiazepine Gaba Receptors .
GABA A Receptor .
GABA A Receptor alpha Subunit .
GABA A Receptor beta Subunit .
GABA A Receptor delta Subunit .
GABA A Receptor epsilon Subunit .
GABA A Receptor gamma Subunit .
GABA A Receptor rho Subunit .
GABA A Receptors .
GABA Benzodiazepine Receptor .
GABA Benzodiazepine Receptors .
Receptor, Benzodiazepine .
Receptor, Benzodiazepine-GABA .
Receptor, Diazepam .
Receptor, GABA-A .
Receptor, GABA-Benzodiazepine .
Receptor, Muscimol .
Receptors, Benzodiazepine GABA .
Receptors, GABA A .
Receptors, GABA Benzodiazepine .
delta Subunit, GABA A Receptor .
epsilon Subunit, GABA A Receptor .
gamma Aminobutyric Acid Subtype A Receptors .
Receptors, GABA-Benzodiazepine .
Benzodiazepine-Gaba Receptors .
GABA-A Receptors .
Receptors, Benzodiazepine-GABA .
Receptors, Benzodiazepine .
Receptors, Diazepam .
Receptors, Muscimol .
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop. .
0.40
5818006