serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.033 Alcohols .
D02.033.800 Sugar Alcohols .
D02.033.800.813 Sorbitol .
D02.033.800.813.480 Isosorbide .
D02.033.800.813.480.500 Isosorbide Dinitrate .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.725 Pyridines .
D03.383.725.203 Dihydropyridines .
D03.383.725.203.540 Nifedipine .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.079 Benzazepines .
D03.633.100.079.080 Benzodiazepines .
D03.633.100.079.080.070 Benzodiazepinones .
D03.633.100.079.080.070.216 Diazepam .
D03.633.100.079.080.070.305 Flumazenil .
D03.633.100.079.150 Diltiazem .
D05 Macromolecular Substances .
D05.750 Polymers .
D05.750.078 Biopolymers .
D05.750.078.730 Microfilament Proteins .
D05.750.078.730.212 Actin Depolymerizing Factors .
D05.750.078.730.212.750 Cofilin 2 .
D09 Carbohydrates .
D09.853 Sugar Alcohols .
D09.853.813 Sorbitol .
D09.853.813.480 Isosorbide .
D09.853.813.480.500 Isosorbide Dinitrate .
D10 Lipids .
D10.251 Fatty Acids .
D10.251.355 Fatty Acids, Unsaturated .
D10.251.355.255 Eicosanoids .
D10.251.355.255.550 Prostaglandins .
D10.251.355.255.550.400 Prostaglandins F .
D10.251.355.255.550.400.200 Dinoprost .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.210 Contractile Proteins .
D12.776.210.500 Muscle Proteins .
D12.776.210.500.242 Cofilin 2 .
D12.776.220 Cytoskeletal Proteins .
D12.776.220.525 Microfilament Proteins .
D12.776.220.525.212 Actin Depolymerizing Factors .
D12.776.220.525.212.750 Cofilin 2 .
D23 Biological Factors .
D23.469 Inflammation Mediators .
D23.469.050 Autacoids .
D23.469.050.175 Eicosanoids .
D23.469.050.175.725 Prostaglandins .
D23.469.050.175.725.400 Prostaglandins F .
D23.469.050.175.725.400.200 Dinoprost .
E05 Investigative Techniques .
E05.284 Dilatation .
G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.820 Signal Transduction .
G04 Cell Physiological Phenomena .
G04.835 Signal Transduction .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Diltiazem .
Aldizem .
CRD-401 .
Cardil .
Cardizem .
Dilacor .
Dilacor XR .
Dilren .
Diltiazem Hydrochloride .
Diltiazem Malate .
Dilzem .
Tiazac .
CRD 401 .
CRD401 .
A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions. .
1.00
866050
 
Isosorbide Dinitrate .
Cardonit 40 .
Dilatrate .
Iso-Bid .
Isodinit .
Isoket .
Isoket Retard-120 .
Isomak R .
Isordil .
Isotrate .
Nitrosorbide .
Sorbitrate .
Sorbonit .
Dinitrate, Isosorbide .
Iso Bid .
IsoBid .
Isoket Retard 120 .
Isoket Retard120 .
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action. .
0.39
513460
 
Diazepam .
7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one .
Apaurin .
Diazemuls .
Faustan .
Relanium .
Seduxen .
Sibazon .
Stesolid .
Valium .
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity. .
0.34
29916986
 
Cofilin 2 .
CFL2 Protein .
Cofilin-2 .
M-Cofilin .
Muscle Cofilin .
Cofilin, Muscle .
A member of the cofilin family of proteins that is expressed in MUSCLE CELLS. It has ACTIN depolymerization activity that is dependent on HYDROGEN-ION CONCENTRATION. .
0.32
066
 
Nifedipine .
Adalat .
BAY-a-1040 .
Bay-1040 .
Cordipin .
Cordipine .
Corinfar .
Fenigidin .
Korinfar .
Nifangin .
Nifedipine Monohydrochloride .
Nifedipine-GTIS .
Procardia .
Procardia XL .
Vascard .
BAY a 1040 .
BAYa1040 .
Bay 1040 .
Bay1040 .
Monohydrochloride, Nifedipine .
Nifedipine GTIS .
A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure. .
0.32
36815288
 
Flumazenil .
Anexate .
Lanexat .
Ro 15-1788 .
Romazicon .
Ro 15 1788 .
Ro 151788 .
Flumazepil .
RO 15-1788 .
A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses. .
0.32
463355
 
Dinoprost .
9alpha,11beta-PGF2 .
Enzaprost F .
Estrofan .
PGF2 alpha .
Prostaglandin F2 alpha .
9alpha,11beta PGF2 .
F2 alpha, Prostaglandin .
F2alpha, Prostaglandin .
alpha, PGF2 .
PGF2 13201 .
PGF2alpha .
Prostaglandin F2 .
Prostaglandin F2alpha .
A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions. .
0.32
2210810
 
/pharmacology .
/mechanism of action .
/mode of action .
/pharmacodynamics .
/pharmacologic action .
Used with drugs and exogenously administered chemical substances for their effects on living tissues and organisms. It includes acceleration and inhibition of physiological and biochemical processes and other pharmacologic mechanisms of action. .
0.32
 
Signal Transduction .
Receptor Mediated Signal Transduction .
Signal Transduction Pathways .
Signal Transduction Systems .
Pathway, Signal .
Pathway, Signal Transduction .
Pathways, Signal .
Pathways, Signal Transduction .
Receptor-Mediated Signal Transductions .
Signal Pathway .
Signal Transduction Pathway .
Signal Transduction System .
Signal Transduction, Receptor-Mediated .
Signal Transductions .
Signal Transductions, Receptor-Mediated .
System, Signal Transduction .
Systems, Signal Transduction .
Transduction, Signal .
Transductions, Signal .
Receptor-Mediated Signal Transduction .
Signal Pathways .
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. .
0.32
393345469
 
Dilatation .
Dilation .
Dilatations .
Dilations .
The act of dilating. .
0.32
1329140