serw-MX  [xml]  
 
    
 DeCS Categories

D01 Inorganic Chemicals .
D01.029 Acids .
D01.029.260 Acids, Noncarboxylic .
D01.029.260.110 Boronic Acids .
D01.029.260.110.500 Bortezomib .
D01.132 Boron Compounds .
D01.132.285 Boronic Acids .
D01.132.285.500 Bortezomib .
D01.210 Chlorine Compounds .
D01.210.375 Cisplatin .
D01.625 Nitrogen Compounds .
D01.625.125 Cisplatin .
D01.710 Platinum Compounds .
D01.710.100 Cisplatin .
D02 Organic Chemicals .
D02.203 Boron Compounds .
D02.203.200 Boronic Acids .
D02.203.200.500 Bortezomib .
D02.241 Carboxylic Acids .
D02.241.081 Acids, Acyclic .
D02.241.081.114 Butyrates .
D02.241.081.114.625 Bendamustine Hydrochloride .
D02.455 Hydrocarbons .
D02.455.326 Hydrocarbons, Acyclic .
D02.455.326.146 Alkanes .
D02.455.326.146.100 Alkanesulfonic Acids .
D02.455.326.146.100.050 Alkanesulfonates .
D02.455.326.146.100.050.500 Mesylates .
D02.455.326.146.100.050.500.300 Ethyl Methanesulfonate .
D02.455.326.146.100.050.500.500 Methyl Methanesulfonate .
D02.455.526 Hydrocarbons, Halogenated .
D02.455.526.728 Mustard Compounds .
D02.455.526.728.650 Nitrogen Mustard Compounds .
D02.455.526.728.650.103 Bendamustine Hydrochloride .
D02.455.526.728.650.529 Mechlorethamine .
D02.806 Quinones .
D02.806.400 Indolequinones .
D02.806.400.249 Mitomycins .
D02.806.400.249.350 Mitomycin .
D02.886 Sulfur Compounds .
D02.886.645 Sulfur Acids .
D02.886.645.600 Sulfonic Acids .
D02.886.645.600.055 Alkanesulfonic Acids .
D02.886.645.600.055.050 Alkanesulfonates .
D02.886.645.600.055.050.510 Mesylates .
D02.886.645.600.055.050.510.300 Ethyl Methanesulfonate .
D02.886.645.600.055.050.510.500 Methyl Methanesulfonate .
D03 Heterocyclic Compounds .
D03.132 Alkaloids .
D03.132.206 Cinchona Alkaloids .
D03.132.206.719 Quinine .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.097 Azirines .
D03.383.097.500 Mitomycins .
D03.383.097.500.350 Mitomycin .
D03.383.679 Pyrazines .
D03.383.679.450 Bortezomib .
D03.605 Heterocyclic Compounds, Bridged-Ring .
D03.605.687 Quinuclidines .
D03.605.687.762 Quinine .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.103 Benzimidazoles .
D03.633.100.103.123 Bendamustine Hydrochloride .
D03.633.100.473 Indoles .
D03.633.100.473.412 Indolequinones .
D03.633.100.473.412.249 Mitomycins .
D03.633.100.473.412.249.350 Mitomycin .
D03.633.100.810 Quinolines .
D03.633.100.810.762 Quinine .
D03.633.300 Heterocyclic Compounds, 3-Ring .
D03.633.300.046 Acridines .
D03.633.300.046.250 Aminoacridines .
D03.633.300.046.250.225 Amsacrine .
D13 Nucleic Acids, Nucleotides, and Nucleosides .
D13.444 Nucleic Acids .
D13.444.308 DNA 12232 .
D13.444.308.135 DNA Adducts .
G05 Genetic Phenomena .
G05.200 DNA Damage .
G05.200.104 DNA Adducts .
 
 Terms
 Synonyms & Historicals		Documents
LILACS e MDL		 
Mechlorethamine .
Bis(2-chloroethyl)methylamine .
Caryolysine .
Cloramin .
Embichin .
Mechlorethamine Hydrochloride .
Mechlorethamine Hydrochloride N-Oxide .
Mechlorethamine N-Oxide .
Methylchlorethamine .
Mitomen .
Mustargen .
NSC-10107 .
NSC-762 .
Nitrogranulogen .
Nitromin .
Hydrochloride N-Oxide, Mechlorethamine .
Hydrochloride, Mechlorethamine .
Mechlorethamine Hydrochloride N Oxide .
Mechlorethamine N Oxide .
N-Oxide, Mechlorethamine Hydrochloride .
N-Oxide, Nitrogen Mustard .
NSC 10107 .
NSC 762 .
NSC10107 .
NSC762 .
Nitrogen Mustard N Oxide .
Chlorethazine .
Chlormethine .
Mechlorethamine Oxide .
Mustine .
Nitrogen Mustard .
Nitrogen Mustard N-Oxide .
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. .
1.00
123102
 
Bendamustine Hydrochloride .
Bendamustin .
Bendamustine .
Cytostasan .
IMET 3393 .
Ribomustin .
Treanda .
Zimet 3393 .
Hydrochloride, Bendamustine .
A nitrogen mustard compound that functions as an ALKYLATING ANTINEOPLASTIC AGENT and is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA and NON-HODGKIN'S LYMPHOMA. .
0.44
1571
 
Ethyl Methanesulfonate .
Ethyl Mesilate .
Ethyl Mesylate .
Ethylmesilate .
Ethylmesylate .
Mesilate, Ethyl .
Mesylate, Ethyl .
Methanesulfonate, Ethyl .
Sulfonate, Ethylmethane .
Ethylmethane Sulfonate .
An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect. .
0.41
71879
 
Mitomycin .
Ametycine .
Mitocin-C .
Mitomycin-C .
Mutamycin .
NSC-26980 .
Mitocin C .
MitocinC .
NSC 26980 .
NSC26980 .
Mitomycin C .
MITOMYCINA .
An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis. .
0.38
17311230
 
Methyl Methanesulfonate .
Dimethylsulfonate .
Mesilate, Methyl .
Methyl Mesylate .
Methyl Methylenesulfonate .
Methylmesilate .
Mesylate, Methyl .
Methanesulfonate, Methyl .
Methyl Mesilate .
Methylmethane Sulfonate .
An alkylating agent in cancer therapy that may also act as a mutagen by interfering with and causing damage to DNA. .
0.37
32318
 
Quinine .
Biquinate .
Legatrim .
Myoquin .
Quinamm .
Quinbisan .
Quinbisul .
Quindan .
Quinimax .
Quinine Bisulfate .
Quinine Hydrochloride .
Quinine Lafran .
Quinine Sulfate .
Quinine Sulphate .
Quinine-Odan .
Quinoctal .
Quinson .
Quinsul .
Strema .
Surquina .
Bisulfate, Quinine .
Hydrochloride, Quinine .
Sulfate, Quinine .
Sulphate, Quinine .
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood. .
0.36
705399
 
Cisplatin .
Biocisplatinum .
Dichlorodiammineplatinum .
NSC-119875 .
Platidiam .
Platino .
Platinol .
cis-Diamminedichloroplatinum .
cis-Platinum .
Diamminodichloride, Platinum .
cis Diamminedichloroplatinum .
cis Platinum .
cis-Diamminedichloroplatinum(II) .
cis-Dichlorodiammineplatinum(II) .
Platinum Diamminodichloride .
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle. .
0.36
25146678
 
Amsacrine .
AMSA 11704 .
AMSA P-D .
Amsacrina .
Amsidine .
Amsidyl .
Cain's Acridine .
NSC-141549 .
NSC-156303 .
NSC-249992 .
SN-11841 .
SN11841 .
meta-AMSA .
AMSA P D .
AMSA PD .
Cain Acridine .
Cains Acridine .
NSC 141549 .
NSC 156303 .
NSC 249992 .
NSC141549 .
NSC156303 .
NSC249992 .
SN 11841 .
meta AMSA .
m-AMSA .
An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent. .
0.35
21147
 
Bortezomib .
LDP-341 .
PS 341 .
PS-341 .
Velcade .
341, PS .
LDP 341 .
LDP341 .
PS341 .
A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of MULTIPLE MYELOMA and MANTLE CELL LYMPHOMA. .
0.35
154609
 
DNA Adducts .
Adducts, DNA .
The products of chemical reactions that result in the addition of extraneous chemical groups to DNA. .
0.35
137531