Cytochrome P450 Family 21. CYP21 Enzymes . CYP21 Family . A cytochrome P450 enzyme family that includes STEROID 21-HYDROXYLASE, which functions in the biosynthesis of STEROIDS. . 1.00
Cytochrome P450 Family 17. CYP17 Enzymes . CYP17 Family . A cytochrome P450 enzyme family that functions in the biosynthesis of STEROIDS and includes STEROID 17-ALPHA-HYDROXYLASE. . 0.85
Cytochrome P450 Family 19. CYP19 Enzymes . CYP19 Family . A cytochrome P450 enzyme family that includes AROMATASE, which functions in the biosynthesis of ESTROGENS. . 0.66
Cytochrome P450 Family 2. CYP2 Enzymes . CYP2 Family . A cytochrome P450 enzyme family that includes members which function in the metabolism of STEROIDS; COUMARINS; and NICOTINE. . 0.62
Cytochrome P450 Family 8. CYP8 Enzymes . CYP8 Family . A cytochrome P450 enzyme family whose members include prostacyclin synthase and STEROID 12-ALPHA-HYDROXYLASE, which function in the biosynthesis of BILE ACIDS. . 0.59
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Steroid 21-Hydroxylase. 21-Hydroxylase . Cytochrome P-450 21-Hydroxylase . Cytochrome P-450 c21 . Cytochrome P-450(c-21) . Cytochrome P450c21 . Progesterone 21-Hydroxylase . Steroid-21-Hydroxylase . 21 Hydroxylase . Cytochrome P 450 21 Hydroxylase . Cytochrome P 450 CYP21 . Cytochrome P 450 c21 . P-450 c21, Cytochrome . Progesterone 21 Hydroxylase . Steroid 21 Hydroxylase . Steroid 21 Monooxygenase . Cytochrome P-450 CYP21 . Steroid 21-Monooxygenase . CYTOCHROME P-450(C-21) . An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). . 0.51
Cytochrome P450 Family 3. CYP3 Enzymes . CYP3 Family . A cytochrome P450 enzyme family that includes members with critical functions in the metabolism of drugs and SEX HORMONES. . 0.49
