Cytochrome P450 Family 26. CYP26 Cytochrome P450 . CYP26 Enzymes . CYP26 Family . Cytochrome P-450 CYP26 . Cytochrome P 450 CYP26 . Cytochrome P450, CYP26 . A cytochrome P450 enzyme family whose members function in the metabolism of RETINOIC ACID. It includes RETINOIC ACID 4-HYDROXYLASE. . 1.00
Tretinoin. Retin-A . Tretinoin Potassium Salt . Tretinoin Sodium Salt . Tretinoin Zinc Salt . Vesanoid . all-trans-Retinoic Acid . beta-all-trans-Retinoic Acid . trans-Retinoic Acid . Acid, Retinoic . Acid, Vitamin A . Acid, all-trans-Retinoic . Acid, beta-all-trans-Retinoic . Acid, trans-Retinoic . Potassium Salt, Tretinoin . Retin A . Salt, Tretinoin Potassium . Salt, Tretinoin Sodium . Salt, Tretinoin Zinc . Sodium Salt, Tretinoin . Zinc Salt, Tretinoin . all trans Retinoic Acid . beta all trans Retinoic Acid . trans Retinoic Acid . Retinoic Acid . Vitamin A Acid . An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). . 0.57
Cytochrome P450 Family 27. CYP27 Enzymes . CYP27 Family . A cytochrome P450 enzyme family whose members function in VITAMIN D metabolism and the biosynthesis of BILE ACIDS. . 0.56
Cytochrome P450 Family 4. CYP4 Enzymes . CYP4 Family . A cytochrome P450 enzyme family that includes members which function in the metabolism of FATTY ACIDS, especially ARACHIDONIC ACIDS and their derivatives. . 0.54
Cytochrome P450 Family 1. CYP1 Enzymes . CYP1 Family . A cytochrome P450 enzyme family whose members function primarily in the metabolism of XENOBIOTICS, including drugs and POLYCYCLIC AROMATIC HYDROCARBONS. . 0.51
Cytochrome P450 Family 8. CYP8 Enzymes . CYP8 Family . A cytochrome P450 enzyme family whose members include prostacyclin synthase and STEROID 12-ALPHA-HYDROXYLASE, which function in the biosynthesis of BILE ACIDS. . 0.50