serw-MX  [xml]  
 


    
 DeCS Categories

C01 Bacterial Infections and Mycoses .
C01.252 Bacterial Infections .
C01.252.410 Gram-Positive Bacterial Infections .
C01.252.410.222 Clostridium Infections .
C01.252.410.222.864 Tetanus .
C10 Nervous System Diseases .
C10.597 Neurologic Manifestations .
C10.597.613 Neuromuscular Manifestations .
C10.597.613.875 Tetany .
C18 Nutritional and Metabolic Diseases .
C18.452 Metabolic Diseases .
C18.452.174 Calcium Metabolism Disorders .
C18.452.174.509 Hypocalcemia .
C18.452.174.509.700 Tetany .
C23 Pathological Conditions, Signs and Symptoms .
C23.888 Signs and Symptoms .
C23.888.592 Neurologic Manifestations .
C23.888.592.608 Neuromuscular Manifestations .
C23.888.592.608.875 Tetany .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.097 Bacterial Proteins .
D12.776.097.872 Tetanus Toxin .
D20 Complex Mixtures .
D20.215 Biological Products .
D20.215.894 Vaccines .
D20.215.894.691 Toxoids .
D20.215.894.691.824 Tetanus Toxoid .
D23 Biological Factors .
D23.946 Toxins, Biological .
D23.946.123 Bacterial Toxins .
D23.946.123.893 Tetanus Toxin .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Tetanus .
Clostridium tetani Infection .
Clostridium tetani Infections .
Infection, Clostridium tetani .
Infections, Clostridium tetani .
A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form. .
1.00
 
Tetanus Toxin .
Tetanus Toxins .
Neurotoxin, Clostridial .
Toxin, Clostridium tetani .
Toxin, Tetanus .
Toxins, Tetanus .
Clostridial Neurotoxin .
Clostridium tetani Toxin .
Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS. .
0.45
162228
 
Tetanus Toxoid .
Toxoid, Tetanus .
Vaccine, Tetanus .
Tetanus Vaccine .
0.42
1306293
 
Tetany .
Tetanilla .
Neonatal Tetanies .
Neonatal Tetany .
Spasmophilias .
Tetanies .
Tetanies, Neonatal .
Tetanillas .
Spasmophilia .
Tetany, Neonatal .
A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This condition is associated with unstable depolarization of axonal membranes, primarily in the peripheral nervous system. Tetany usually results from HYPOCALCEMIA or reduced serum levels of MAGNESIUM that may be associated with HYPERVENTILATION; HYPOPARATHYROIDISM; RICKETS; UREMIA; or other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1490) .
0.42
161550