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A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley s anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent CID10 - Classificação Internacional de Doenças DeCS Português DeCS Inglês DeCS Espanhol DeCS Espanha DeCS Português com escopo DeCS Inglês com escopo DeCS Espanhol com escopo DeCS Espanha com escopo LILACS - LILACS Regional
DeCS Categories C15 Hemic and Lymphatic Diseases . C15.378 Hematologic Diseases . C15.378.071 Anemia . C15.378.071.141 Anemia, Hemolytic . C15.378.071.141.150 Anemia, Hemolytic, Congenital . C15.378.071.141.150.150 Anemia, Sickle Cell . C15.378.071.141.150.150.670 Sickle Cell Trait . C15.378.071.141.150.875 Thalassemia . C15.378.071.141.150.875.150 beta-Thalassemia . C15.378.071.141.150.875.575 delta-Thalassemia . C15.378.420 Hemoglobinopathies . C15.378.420.155 Anemia, Sickle Cell . C15.378.420.155.668 Sickle Cell Trait . C15.378.420.826 Thalassemia . C15.378.420.826.150 beta-Thalassemia . C15.378.420.826.200 delta-Thalassemia . C15.378.619 Methemoglobinemia . C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities . C16.320 Genetic Diseases, Inborn . C16.320.070 Anemia, Hemolytic, Congenital . C16.320.070.150 Anemia, Sickle Cell . C16.320.070.150.670 Sickle Cell Trait . C16.320.070.875 Thalassemia . C16.320.070.875.150 beta-Thalassemia . C16.320.070.875.575 delta-Thalassemia . C16.320.365 Hemoglobinopathies . C16.320.365.155 Anemia, Sickle Cell . C16.320.365.155.668 Sickle Cell Trait . C16.320.365.826 Thalassemia . C16.320.365.826.150 beta-Thalassemia . C16.320.365.826.575 delta-Thalassemia . D12 Amino Acids, Peptides, and Proteins . D12.776 Proteins . D12.776.124 Blood Proteins . D12.776.124.400 Hemoglobins . D12.776.124.400.405 Hemoglobin A . D12.776.124.400.463 Hemoglobins, Abnormal . D12.776.124.400.463.510 Hemoglobin M . D12.776.422 Hemeproteins . D12.776.422.316 Globins . D12.776.422.316.762 Hemoglobins . D12.776.422.316.762.380 Hemoglobin A . D12.776.422.316.762.426 Hemoglobins, Abnormal . D12.776.422.316.762.426.510 Hemoglobin M .		Terms  Synonyms & Historicals Documents LILACS e MDL   beta-Thalassemia . Erythroblastic Anemia . Mediterranean Anemia . Microcytemia, beta Type . Thalassemia Intermedia . Thalassemia Major (beta-Thalassemia Major) . Thalassemia Minor (beta-Thalassemia Minor) . Thalassemia, beta Type . beta Thalassemia . Anemia, Cooley . Anemia, Cooleys . Anemias, Erythroblastic . Anemias, Mediterranean . Cooley's Anemia . Disease, Hemoglobin F . Intermedia, Thalassemia . Intermedias, Thalassemia . Major, Thalassemia (beta-Thalassemia Major) . Majors, Thalassemia (beta-Thalassemia Major) . Mediterranean Anemias . Microcytemias, beta Type . Minor, Thalassemia (beta-Thalassemia Minor) . Minors, Thalassemia (beta-Thalassemia Minor) . Thalassemia Intermedias . Thalassemia Major (beta Thalassemia Major) . Thalassemia Majors (beta-Thalassemia Major) . Thalassemia Minor (beta Thalassemia Minor) . Thalassemia Minors (beta-Thalassemia Minor) . Thalassemia, beta . Thalassemias, beta . Thalassemias, beta Type . Type Microcytemia, beta . Type Microcytemias, beta . Type Thalassemia, beta . Type Thalassemias, beta . beta Thalassemias . beta Type Microcytemia . beta Type Microcytemias . beta Type Thalassemia . beta Type Thalassemias . Anemia, Cooley's . Anemia, Erythroblastic . Anemia, Mediterranean . Hemoglobin F Disease . Thalassemia Major . Thalassemia Minor . A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent. . 1.00 100 6821   Hemoglobin A . Normal adult human hemoglobin. The globin moiety consists of two alpha and two beta chains. . 0.44 62 3144   Hemoglobins . Eryhem . Ferrous Hemoglobin . Hemoglobin . Hemoglobin, Ferrous . The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. . 0.43 769 58519   Methemoglobinemia . Methemoglobinemias . The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed) . 0.42 62 2465   Sickle Cell Trait . Cell Trait, Sickle . Cell Traits, Sickle . Sickle Cell Traits . Trait, Sickle Cell . Traits, Sickle Cell . The condition of being heterozygous for hemoglobin S. . 0.41 91 1948   delta-Thalassemia . delta Thalassemia . delta-Thalassemias . A hereditary disorder characterized by reduced or absent DELTA-GLOBIN thus effecting the level of HEMOGLOBIN A2, a minor component of adult hemoglobin monitored in the diagnosis of BETA-THALASSEMIA. . 0.40 0 37   Hemoglobin M . A group of abnormal hemoglobins in which amino acid substitutions take place in either the alpha or beta chains but near the heme iron. This results in facilitated oxidation of the hemoglobin to yield excess methemoglobin which leads to cyanosis. . 0.39 2 125   Thalassemia . Thalassemias . A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia. . 0.39 170 9700