serw-MX  [xml]  
 


    
 DeCS Categories

C23 Pathological Conditions, Signs and Symptoms .
C23.550 Pathologic Processes .
C23.550.717 Necrosis .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.276 Intercellular Signaling Peptides and Proteins .
D12.644.276.374 Cytokines .
D12.644.276.374.500 Monokines .
D12.644.276.374.500.800 Tumor Necrosis Factor-alpha .
D12.644.276.374.750 Tumor Necrosis Factors .
D12.644.276.374.750.626 Tumor Necrosis Factor-alpha .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.900 Tumor Necrosis Factor-alpha .
D12.776.395 Glycoproteins .
D12.776.395.930 Tumor Necrosis Factor-alpha .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.374 Cytokines .
D12.776.467.374.500 Monokines .
D12.776.467.374.500.800 Tumor Necrosis Factor-alpha .
D12.776.467.374.750 Tumor Necrosis Factors .
D12.776.467.374.750.626 Tumor Necrosis Factor-alpha .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.690 Receptors, Death Domain .
D12.776.543.750.690.750 Receptors, Tumor Necrosis Factor, Type I .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.852 Receptors, Cytokine .
D12.776.543.750.705.852.760 Receptors, Tumor Necrosis Factor .
D12.776.543.750.705.852.760.597 Receptors, Tumor Necrosis Factor, Type I .
D23 Biological Factors .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.374 Cytokines .
D23.529.374.500 Monokines .
D23.529.374.500.800 Tumor Necrosis Factor-alpha .
D23.529.374.750 Tumor Necrosis Factors .
D23.529.374.750.626 Tumor Necrosis Factor-alpha .
G04 Cell Physiological Phenomena .
G04.146 Cell Death .
G04.146.638 Necrosis .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Tumor Necrosis Factors .
TNF Receptor Ligands .
Tumor Necrosis Factor Superfamily Ligands .
Necrosis Factors, Tumor .
Receptor Ligands, TNF .
TNF 26382 .
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. .
1.00
482038
 
Necrosis .
Necroses .
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process. .
0.51
92152279
 
Tumor Necrosis Factor-alpha .
Cachectin-Tumor Necrosis Factor .
TNF Superfamily, Member 2 .
TNFalpha .
Tumor Necrosis Factor .
Cachectin Tumor Necrosis Factor .
Tumor Necrosis Factor alpha .
Cachectin .
TNF-alpha .
Tumor Necrosis Factor Ligand Superfamily Member 2 .
Tumor Necrosis Factor .
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. .
0.48
794111894
 
Receptors, Tumor Necrosis Factor .
Receptors, Cachectin .
Receptors, TNF .
TNF Receptor .
Tumor Necrosis Factor Receptor .
Receptor, TNF .
Cachectin Receptors .
Tumor Necrosis Factor Receptors .
TNF Receptors .
TNFR 19189 .
Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells. .
0.47
4414490
 
Receptors, Tumor Necrosis Factor, Type I .
CD 120a Antigen .
CD120a Antigen .
TNFR p60 .
TNFR-I .
TNFR1 .
TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A) .
TNFRSF1A Receptor .
Tumor Necrosis Factor Receptor 1A .
Tumor Necrosis Factor Receptor Type 1 .
120a Antigen, CD .
Antigen, CD 120a .
Antigen, CD120a .
Receptor, TNFRSF1A .
Antigens, CD120a .
CD120a Antigens .
Receptors, Tumor Necrosis Factor, Member 1A .
Tumor Necrosis Factor Receptor Superfamily, Member 1A .
Tumor Necrosis Factor Receptor Type I .
A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. .
0.44
143882