serw-MX  [xml]  

 DeCS Categories

C12 Male Urogenital Diseases .
C12.777 Urologic Diseases .
C12.777.934 Urination Disorders .
C12.777.934.734 Proteinuria .
C12.777.934.734.634 Hemoglobinuria .
C13 Female Urogenital Diseases and Pregnancy Complications .
C13.351 Female Urogenital Diseases .
C13.351.968 Urologic Diseases .
C13.351.968.934 Urination Disorders .
C13.351.968.934.734 Proteinuria .
C13.351.968.934.734.634 Hemoglobinuria .
C15 Hemic and Lymphatic Diseases .
C15.378 Hematologic Diseases .
C15.378.619 Methemoglobinemia .
C23 Pathological Conditions, Signs and Symptoms .
C23.888 Signs and Symptoms .
C23.888.248 Cyanosis .
C23.888.942 Urological Manifestations .
C23.888.942.750 Proteinuria .
C23.888.942.750.634 Hemoglobinuria .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.400 Hemoglobins .
D12.776.124.400.405 Hemoglobin A .
D12.776.124.400.463 Hemoglobins, Abnormal .
D12.776.124.400.463.480 Hemoglobin J .
D12.776.124.400.463.510 Hemoglobin M .
D12.776.124.400.599 Methemoglobin .
D12.776.422 Hemeproteins .
D12.776.422.316 Globins .
D12.776.422.316.762 Hemoglobins .
D12.776.422.316.762.380 Hemoglobin A .
D12.776.422.316.762.426 Hemoglobins, Abnormal .
D12.776.422.316.762.426.480 Hemoglobin J .
D12.776.422.316.762.426.510 Hemoglobin M .
D12.776.422.316.762.571 Methemoglobin .
 Synonyms & Historicals
Hemoglobin M .
A group of abnormal hemoglobins in which amino acid substitutions take place in either the alpha or beta chains but near the heme iron. This results in facilitated oxidation of the hemoglobin to yield excess methemoglobin which leads to cyanosis. .
Methemoglobinemia .
Methemoglobinemias .
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed) .
Hemoglobins .
Eryhem .
Ferrous Hemoglobin .
Hemoglobin .
Hemoglobin, Ferrous .
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. .
Hemoglobin J .
A group of abnormal hemoglobins with similar electrophoretic characteristics. They have faster electrophoretic mobility and different amino acid substitutions in either the alpha or beta chains than normal adult hemoglobin. Some of the variants produce hematologic abnormalities, others result in no clinical disorders. .
Methemoglobin .
Ferrihemoglobin .
Hemoglobin A .
Normal adult human hemoglobin. The globin moiety consists of two alpha and two beta chains. .
Hemoglobinuria .
The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine. .
Cyanosis .
Cyanoses .
A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule. .