serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.092 Amines .
D02.092.877 Quaternary Ammonium Compounds .
D02.092.877.096 Benzylammonium Compounds .
D02.092.877.096.333 Bretylium Compounds .
D02.092.877.096.333.150 Bretylium Tosylate .
D02.455 Hydrocarbons .
D02.455.326 Hydrocarbons, Acyclic .
D02.455.326.146 Alkanes .
D02.455.326.146.100 Alkanesulfonic Acids .
D02.455.326.146.100.050 Alkanesulfonates .
D02.455.326.146.100.050.500 Mesylates .
D02.455.326.146.100.050.500.300 Ethyl Methanesulfonate .
D02.455.526 Hydrocarbons, Halogenated .
D02.455.526.728 Mustard Compounds .
D02.455.526.728.650 Nitrogen Mustard Compounds .
D02.455.526.728.650.463 Mannomustine .
D02.886 Sulfur Compounds .
D02.886.645 Sulfur Acids .
D02.886.645.600 Sulfonic Acids .
D02.886.645.600.055 Alkanesulfonic Acids .
D02.886.645.600.055.050 Alkanesulfonates .
D02.886.645.600.055.050.510 Mesylates .
D02.886.645.600.055.050.510.300 Ethyl Methanesulfonate .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.124 Alkylating Agents .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.399 Hormones, Hormone Substitutes, and Hormone Antagonists .
D27.505.696.399.472 Hormones .
D27.505.696.399.472.161 Androgens .
D27.505.696.706 Protective Agents .
D27.505.696.706.080 Antimutagenic Agents .
D27.505.954 Therapeutic Uses .
D27.505.954.248 Antineoplastic Agents .
D27.720 Specialty Uses of Chemicals .
D27.720.799 Protective Agents .
D27.720.799.042 Antimutagenic Agents .
D27.888 Toxic Actions .
D27.888.569 Noxae .
D27.888.569.035 Alkylating Agents .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Nitrogen Mustard Compounds .
Compounds, Nitrogen Mustard .
Mustard Compounds, Nitrogen .
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. .
1.00
02859
 
Alkylating Agents .
Alkylators .
Agents, Alkylating .
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. .
0.48
406645
 
Mannomustine .
Decranol .
Degranol .
Mannitlost .
Mannitol Mustard .
Mustard, Mannitol .
Mustard, Mannitol Nitrogen .
Nitrogen Mustard, Mannitol .
Mannitol Nitrogen Mustard .
Nitrogen mustard derivative alkylating agent used as antineoplastic. It causes severe bone marrow depression and is a powerful vesicant. .
0.39
1103
 
Bretylium Tosylate .
Bretylate .
Bretylium Tosilate .
Bretylol .
Ornid .
An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now proposed as an anti-arrhythmic. .
0.38
4262
 
Antineoplastic Agents .
Anticancer Agents .
Antineoplastic Drugs .
Antineoplastics .
Antitumor Agents .
Antitumor Drugs .
Cancer Chemotherapy Agents .
Cancer Chemotherapy Drugs .
Chemotherapeutic Anticancer Agents .
Chemotherapeutic Anticancer Drug .
Agents, Anticancer .
Agents, Antineoplastic .
Agents, Antitumor .
Agents, Cancer Chemotherapy .
Agents, Chemotherapeutic Anticancer .
Chemotherapy Agents, Cancer .
Chemotherapy Drugs, Cancer .
Drug, Chemotherapeutic Anticancer .
Drugs, Antineoplastic .
Drugs, Antitumor .
Drugs, Cancer Chemotherapy .
Antineoplastic and Immunosuppressive Agents .
Antineoplastics, Immunosuppressives .
Substances that inhibit or prevent the proliferation of NEOPLASMS. .
0.37
1115234327
 
Antimutagenic Agents .
Anti-Mutagenic Agents .
Anti-Mutagenic Effect .
Anti-Mutagenic Effects .
Antimutagenic Effect .
Antimutagenic Effects .
Antimutagens .
Agents, Anti-Mutagenic .
Agents, Antimutagenic .
Anti Mutagenic Agents .
Anti Mutagenic Effect .
Anti Mutagenic Effects .
Effect, Anti-Mutagenic .
Effect, Antimutagenic .
Effects, Anti-Mutagenic .
Effects, Antimutagenic .
Agents that reduce the frequency or rate of spontaneous or induced mutations independently of the mechanism involved. .
0.37
272161
 
Ethyl Methanesulfonate .
Ethyl Mesilate .
Ethyl Mesylate .
Ethylmesilate .
Ethylmesylate .
Mesilate, Ethyl .
Mesylate, Ethyl .
Methanesulfonate, Ethyl .
Sulfonate, Ethylmethane .
Ethylmethane Sulfonate .
An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect. .
0.37
71879
 
Androgens .
Androgen Effect .
Androgen Effects .
Androgen Receptor Agonists .
Androgenic Agents .
Androgenic Compounds .
Agents, Androgenic .
Agonists, Androgen Receptor .
Compounds, Androgenic .
Effect, Androgen .
Effects, Androgen .
Receptor Agonists, Androgen .
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power. .
0.37
29722358