gamma-Synuclein. Persyn . Synoretin . gamma Synuclein . A homolog of ALPHA-SYNUCLEIN that plays a role in neurofilament network integrity. It is overexpressed in a variety of human NEOPLASMS and may be involved in modulating AXON architecture during EMBRYONIC DEVELOPMENT and in the adult. Gamma-Synuclein may also activate SIGNAL TRANSDUCTION PATHWAYS associated with ETS-DOMAIN PROTEIN ELK-1. . 1.00
beta-Synuclein. Phosphoneuroprotein 14 . beta Synuclein . A synuclein that is closely related to ALPHA-SYNUCLEIN. It may play a neuroprotective role against some of the toxic effects of aggregated ALPHA-SYNUCLEIN. . 0.35
Synaptogyrins. Cellugyrin . Synaptogyrin . A subfamily of MARVEL domain-containing proteins that are found in SYNAPTIC VESICLES, where they may play a role in modulating neuronal signaling. . 0.35
Syndecan-2. Fibroglycan . Heparan Sulfate Proteoglycan Core Protein . Syndecan 2 . A syndecan that is predominantly expressed during EMBRYONIC DEVELOPMENT. It may play a role in mediating cellular interactions with the EXTRACELLULAR MATRIX and may modulate the signaling activity of certain INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. . 0.35
Patched-2 Receptor. PTCH2 Protein . Patched Homolog-2 . Patched Receptor-2 . Patched-2 Protein . Patched 2 Protein . Patched 2 Receptor . Patched Homolog 2 . Patched Receptor 2 . Receptor, Patched-2 . A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA. . 0.34
Syndecan-3. HB-GAM Receptor . Heparin-Binding Growth Associated Molecule Receptor . N-Syndecan . Syndecan 3 . HB GAM Receptor . Heparin Binding Growth Associated Molecule Receptor . N Syndecan . Receptor, HB-GAM . A syndecan found at high levels in the developing LIMB BUDS. It may play a role in the regulation of MUSCULOSKELETAL DEVELOPMENT by modulating the effects of INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. . 0.32
Cathepsin B. Cathepsin B-Like Proteinase . Cathepsin B1 . Cathepsin B Like Proteinase . Proteinase, Cathepsin B-Like . A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS. . 0.32
GTP-Binding Protein alpha Subunit, Gi2. G Protein Subunit alpha I2 . Galpha(i2) Protein . Galphai2 Protein . Gi2-alpha Protein . GTP Binding Protein alpha Subunit, Gi2 . Gi2 alpha Protein . A PERTUSSIS TOXIN-sensitive GTP-binding protein alpha subunit. It couples with a variety of CELL SURFACE RECEPTORS, has been implicated in INTERLEUKIN-12 production, and may play a role in INFLAMMATORY BOWEL DISEASES. . 0.31
alpha-Synuclein. Non-AB Component of AD Amyloid Protein . Non AB Component of AD Amyloid Protein . alpha Synuclein . A synuclein that is a major component of LEWY BODIES that plays a role in neurodegeneration and neuroprotection. . 0.31
