Sarcoma, Synovial. Sarcomas, Synovial . Synovial Sarcoma . Synovial Sarcomas . Synoviomas . Synovioma . A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363) . 1.00
Retinoblastoma. Eye Cancer, Retinoblastoma . Familial Retinoblastoma . Hereditary Retinoblastoma . Sporadic Retinoblastoma . Familial Retinoblastomas . Glioblastomas, Retinal . Gliomas, Retinal . Hereditary Retinoblastomas . Neuroblastomas, Retinal . Retinal Glioblastoma . Retinal Glioblastomas . Retinal Glioma . Retinal Gliomas . Retinal Neuroblastoma . Retinal Neuroblastomas . Retinoblastoma, Familial . Retinoblastoma, Hereditary . Retinoblastoma, Sporadic . Retinoblastomas . Retinoblastomas, Familial . Retinoblastomas, Hereditary . Retinoblastomas, Sporadic . Sporadic Retinoblastomas . Glioblastoma, Retinal . Glioma, Retinal . Neuroblastoma, Retinal . A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104) . 0.44
Chondroblastoma. Chondroblastomas . A usually benign tumor composed of cells which arise from chondroblasts or their precursors and which tend to differentiate into cartilage cells. It occurs primarily in the epiphyses of adolescents. It is relatively rare and represents less than 2% of all primary bone tumors. The peak incidence is in the second decade of life; it is about twice as common in males as in females. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1846) . 0.42
Carcinoid Tumor. Argentaffinomas . Carcinoid Tumors . Carcinoids . Carcinoids, Goblet Cell . Goblet Cell Carcinoid . Goblet Cell Carcinoids . Tumor, Carcinoid . Tumors, Carcinoid . Argentaffinoma . Carcinoid, Goblet Cell . Carcinoid . A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182) . 0.42
Hemangioblastoma. Multiple Hemangioblastomas . Hemangioblastoma, Multiple . Hemangioblastomas . Hemangioblastomas, Multiple . Multiple Hemangioblastoma . A benign tumor of the nervous system that may occur sporadically or in association with VON HIPPEL-LINDAU DISEASE. It accounts for approximately 2% of intracranial tumors, arising most frequently in the cerebellar hemispheres and vermis. Histologically, the tumors are composed of multiple capillary and sinusoidal channels lined with endothelial cells and clusters of lipid-laden pseudoxanthoma cells. Usually solitary, these tumors can be multiple and may also occur in the brain stem, spinal cord, retina, and supratentorial compartment. Cerebellar hemangioblastomas usually present in the third decade with INTRACRANIAL HYPERTENSION, and ataxia. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2071-2) . 0.41
Sarcoma, Alveolar Soft Part. Alveolar Soft-Part Sarcoma . Alveolar Soft Part Sarcoma . A variety of rare sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. It is a rare tumor, usually occurring between 15 and 35 years of age. It appears in the muscles of the extremities in adults and most commonly in the head and neck regions of children. Though slow-growing, it commonly metastasizes to the lungs, brain, bones, and lymph nodes. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1365) . 0.40
Carcinoma, Mucoepidermoid. Carcinomas, Mucoepidermoid . Mucoepidermoid Carcinoma . Mucoepidermoid Carcinomas . A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240) . 0.40
Rhabdomyosarcoma, Embryonal. Embryonal Rhabdomyosarcoma . Embryonal Rhabdomyosarcomas . Rhabdomyosarcomas, Embryonal . A form of RHABDOMYOSARCOMA arising primarily in the head and neck, especially the orbit, of children below the age of 10. The cells are smaller than those of other rhabdomyosarcomas and are of two basic cell types: spindle cells and round cells. This cancer is highly sensitive to chemotherapy and has a high cure rate with multi-modality therapy. (From Holland et al., Cancer Medicine, 3d ed, p2188) . 0.40
Krukenberg Tumor. Krukenberg Carcinoma . Krukenberg's Tumor . Carcinoma, Krukenberg . Krukenbergs Tumor . Tumor, Krukenberg . Tumor, Krukenberg's . Mucocellular carcinoma of the ovary, usually metastatic from the gastrointestinal tract, characterized by areas of mucoid degeneration and the presence of signet-ring-like cells. It accounts for 30%-40% of metastatic cancers to the ovaries and possibly 1%-2% of all malignant ovarian tumors. The lesions may not be discovered until the primary disease is advanced, and most patients die of their disease within a year. In some cases, a primary tumor is not found. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1685) . 0.39
