serw-MX  [xml]  
 


    
 DeCS Categories

A06 Endocrine System .
A06.407 Endocrine Glands .
A06.407.560 Parathyroid Glands .
C19 Endocrine System Diseases .
C19.642 Parathyroid Diseases .
D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.559 Hydrocarbons, Aromatic .
D02.455.426.559.847 Polycyclic Aromatic Hydrocarbons .
D02.455.426.559.847.638 Naphthalenes .
D02.455.426.559.847.638.183 Cinacalcet Hydrochloride .
D04 Polycyclic Compounds .
D04.615 Polycyclic Aromatic Hydrocarbons .
D04.615.638 Naphthalenes .
D04.615.638.183 Cinacalcet Hydrochloride .
D06 Hormones, Hormone Substitutes, and Hormone Antagonists .
D06.347 Hormone Antagonists .
D06.347.230 Calcimimetic Agents .
D06.472 Hormones .
D06.472.699 Peptide Hormones .
D06.472.699.590 Parathyroid Hormone .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.548 Peptide Hormones .
D12.644.548.587 Parathyroid Hormone .
D12.776 Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.695 Receptors, G-Protein-Coupled .
D12.776.543.750.695.115 Receptors, Calcium-Sensing .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.399 Hormones, Hormone Substitutes, and Hormone Antagonists .
D27.505.696.399.450 Hormone Antagonists .
D27.505.696.399.450.230 Calcimimetic Agents .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Cinacalcet Hydrochloride .
AMG 073 .
AMG073 .
Alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride .
Cinacalcet .
KRN 1493 .
Sensipar .
073, AMG .
1493, KRN .
Hydrochloride, Cinacalcet .
A naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in the treatment of PARATHYROID DISEASES. .
1.00
11769
 
Receptors, Calcium-Sensing .
CASR Protein .
Ca-Sensing Receptors .
Ca2+-Sensing Receptor .
Calcium Receptors .
Calcium-Sensing Receptor Protein .
Calcium-Sensing Receptors .
Extracellular Calcium-Ion Sensing Receptor .
Parathyroid Calcium-Sensing Receptor .
Receptor, Ca-Sensing .
Receptors, Calcium .
Ca Sensing Receptors .
Ca-Sensing Receptor .
Ca2+ Sensing Receptor .
Calcium Sensing Receptor .
Calcium Sensing Receptor Protein .
Calcium Sensing Receptors .
Calcium-Sensing Receptor, Parathyroid .
Extracellular Calcium Ion Sensing Receptor .
Parathyroid Calcium Sensing Receptor .
Receptor Protein, Calcium-Sensing .
Receptor, Ca Sensing .
Receptor, Ca2+-Sensing .
Receptor, Calcium-Sensing .
Receptor, Parathyroid Calcium-Sensing .
Receptors, Ca-Sensing .
Receptors, Calcium Sensing .
Calcium-Sensing Receptor .
A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels. .
0.58
102032
 
Calcimimetic Agents .
Agents, Calcimimetic .
Small organic molecules that act as allosteric activators of the calcium sensing receptor (CaSR) in the PARATHYROID GLANDS and other tissues. They lower the threshold for CaSR activation by extracellular calcium ions and diminish PARATHYROID HORMONE (PTH) release from parathyroid cells. .
0.52
2242
 
Parathyroid Diseases .
Parathyroid Disorders .
Disease, Parathyroid .
Diseases, Parathyroid .
Disorder, Parathyroid .
Disorders, Parathyroid .
Parathyroid Disease .
Parathyroid Disorder .
Pathological processes of the PARATHYROID GLANDS. They usually manifest as hypersecretion or hyposecretion of PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body. .
0.46
351312
 
Parathyroid Hormone .
PTH (1-84) .
PTH(1-34) .
Parathormone .
Parathyrin .
Parathyroid Hormone (1-34) .
Parathyroid Hormone (1-84) .
Parathyroid Hormone Peptide (1-34) .
Hormone, Parathyroid .
Parathyroid Hormones .
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates. .
0.46
26025890
 
Parathyroid Glands .
Gland, Parathyroid .
Glands, Parathyroid .
Parathyroid Gland .
Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body. .
0.44