serw-MX  [xml]  

 DeCS Categories

B01 Eukaryota .
B01.650 Plants .
B01.650.940 Viridiplantae .
B01.650.940.800 Streptophyta .
B01.650.940.800.575 Embryophyta .
B01.650.940.800.575.912 Tracheophyta .
B01.650.940.800.575.912.250 Magnoliopsida .
B01.650.940.800.575.912.250.456 Gentianales .
B01.650.940.800.575.912.250.456.500 Apocynaceae .
B01.650.940.800.575.912.250.456.500.833 Strophanthus .
D04 Polycyclic Compounds .
D04.210 Fused-Ring Compounds .
D04.210.500 Steroids .
D04.210.500.155 Cardanolides .
D04.210.500.155.580 Cardiac Glycosides .
D04.210.500.155.580.130 Cardenolides .
D04.210.500.155.580.130.500 Digitalis Glycosides .
D04.210.500.155.580.130.750 Strophanthins .
D04.210.500.155.580.130.750.600 Ouabain .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.450 Glycoside Hydrolases .
D09 Carbohydrates .
D09.408 Glycosides .
D09.408.180 Cardiac Glycosides .
D09.408.180.261 Digitalis Glycosides .
D09.408.180.810 Strophanthins .
D09.408.180.810.600 Ouabain .
 Synonyms & Historicals
Strophanthins .
Strophanthin .
A number of different cardioactive glycosides obtained from Strophanthus species. OUABAIN is from S. gratus and CYMARINE from S. kombe. They are used like the digitalis glycosides. .
Glycosides .
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed) .
Cardiac Glycosides .
Glycosides, Cardiac .
Steroids, Cardiotonic .
Cardiotonic Steroids .
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose. .
Digitalis Glycosides .
Glycosides, Digitalis .
Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis. .
Strophanthus .
A plant genus of the family APOCYNACEAE that contains OUABAIN cardiac glycosides. .
Ouabain .
Acolongifloroside K .
G Strophanthin .
Acocantherin .
G-Strophanthin .
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. .
Glycoside Hydrolases .
Endoglycosidases .
Exoglycosidases .
Glycohydrolases .
Hydrolases, Glycoside .
Glycosidases .