serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.065 Amides .
D02.065.884 Sulfonamides .
D02.065.884.540 Indapamide .
D02.065.884.600 Metolazone .
D02.886 Sulfur Compounds .
D02.886.590 Sulfones .
D02.886.590.700 Sulfonamides .
D02.886.590.700.540 Indapamide .
D02.886.590.700.600 Metolazone .
D03 Heterocyclic Compounds .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.473 Indoles .
D03.633.100.473.391 Indapamide .
D03.633.100.786 Quinazolines .
D03.633.100.786.830 Quinazolinones .
D03.633.100.786.830.688 Metolazone .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.530 Membrane Transport Proteins .
D12.776.157.530.450 Ion Pumps .
D12.776.157.530.450.625 Symporters .
D12.776.157.530.450.625.374 Sodium Chloride Symporters .
D12.776.157.530.450.625.750 Sodium-Potassium-Chloride Symporters .
D12.776.157.530.937 Solute Carrier Proteins .
D12.776.157.530.937.750 Sodium-Potassium-Chloride Symporters .
D12.776.543 Membrane Proteins .
D12.776.543.585 Membrane Transport Proteins .
D12.776.543.585.450 Ion Pumps .
D12.776.543.585.450.625 Symporters .
D12.776.543.585.450.625.750 Sodium-Potassium-Chloride Symporters .
D12.776.543.585.937 Solute Carrier Proteins .
D12.776.543.585.937.875 Sodium-Potassium-Chloride Symporters .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.562 Membrane Transport Modulators .
D27.505.519.562.812 Sodium Chloride Symporter Inhibitors .
D27.505.519.562.906 Sodium Potassium Chloride Symporter Inhibitors .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.560 Natriuretic Agents .
D27.505.696.560.500 Diuretics .
D27.505.696.560.500.863 Sodium Chloride Symporter Inhibitors .
D27.505.696.560.500.931 Sodium Potassium Chloride Symporter Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Metolazone .
Diulo .
Microx .
Mykrox .
SR-720-22 .
Zaroxolyn .
SR 720 22 .
SR72022 .
A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS. .
1.00
1171
 
Indapamide .
S-1520 .
SE-1520 .
S 1520 .
S1520 .
SE 1520 .
SE1520 .
Metindamide .
A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS. .
0.78
12939
 
Sodium Chloride Symporter Inhibitors .
Benzothiadiazine Diuretics .
Diuretics, Thiazide .
Potassium Depleting Diuretics .
Sodium Chloride Cotransporter Inhibitors .
Thiazide Diuretics .
Thiazide Sensitive NaCl Cotransporter Inhibitors .
Diuretics, Benzothiadiazine .
Diuretics, Potassium Depleting .
Diuretics, Thiazide .
Benzothiadiazine Diuretics .
Thiazide Diuretics .
Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. .
0.50
372838
 
Sodium Chloride Symporters .
Na-Cl-Symporters .
Sodium Chloride Cotransporters .
Sodium-Chloride Cotransporter .
Sodium-Chloride Transporter .
Chloride Cotransporters, Sodium .
Chloride Symporters, Sodium .
Cotransporter, Sodium-Chloride .
Cotransporters, Sodium Chloride .
Na Cl Symporters .
Sodium Chloride Cotransporter .
Sodium Chloride Transporter .
Symporters, Sodium Chloride .
Transporter, Sodium-Chloride .
A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS. .
0.44
1476
 
Sodium Potassium Chloride Symporter Inhibitors .
Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors .
High Ceiling Diuretics .
Loop Diuretics .
Na-K-CL Symporter Inhibitors .
Sodium Potassium Chloride Cotransporter Inhibitors .
Bumetanide Sensitive Na K Cl Transporter Inhibitors .
Ceiling Diuretics, High .
Diuretics, High Ceiling .
Diuretics, Loop .
Inhibitors, Na-K-CL Symporter .
Na K CL Symporter Inhibitors .
Symporter Inhibitors, Na-K-CL .
Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA. .
0.44
2805
 
Sodium-Potassium-Chloride Symporters .
Na(+), K(+), Cl(-)-Cotransporter .
Na-K-Cl-Symporter .
Na-K-Cl-Transporter .
NaCl-KCl Cotransporter .
NaK2Cl Symporter .
SLC12A Transporters .
Sodium, Potassium, Chloride-Cotransporter .
Sodium-Potassium-Chloride Cotransporter .
Solute Carrier Family 12 .
Cotransporter, NaCl-KCl .
Cotransporter, Sodium-Potassium-Chloride .
Cotransporters, Sodium-Potassium-Chloride .
Na K Cl Symporter .
Na K Cl Transporter .
NaCl KCl Cotransporter .
Sodium Potassium Chloride Cotransporter .
Sodium Potassium Chloride Cotransporters .
Sodium Potassium Chloride Symporters .
Symporter, NaK2Cl .
Symporters, Sodium-Potassium-Chloride .
Transporters, SLC12A .
Sodium-Potassium-Chloride Cotransporters .
A subclass of symporters that specifically transport SODIUM CHLORIDE and/or POTASSIUM CHLORIDE across cellular membranes in a tightly coupled process. .
0.37
01886