serw-MX  [xml]  
 


    
 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.276 Intercellular Signaling Peptides and Proteins .
D12.644.276.374 Cytokines .
D12.644.276.374.750 Tumor Necrosis Factors .
D12.644.276.374.750.562 RANK Ligand .
D12.644.276.500 Ephrins .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.486 Immunoproteins .
D12.776.124.486.485 Immunoglobulins .
D12.776.124.486.485.114 Antibodies .
D12.776.124.486.485.114.224 Antibodies, Monoclonal .
D12.776.124.486.485.114.224.060 Antibodies, Monoclonal, Humanized .
D12.776.124.486.485.114.224.060.782 Denosumab .
D12.776.124.790 Serum Globulins .
D12.776.124.790.651 Immunoglobulins .
D12.776.124.790.651.114 Antibodies .
D12.776.124.790.651.114.224 Antibodies, Monoclonal .
D12.776.124.790.651.114.224.060 Antibodies, Monoclonal, Humanized .
D12.776.124.790.651.114.224.060.782 Denosumab .
D12.776.377 Globulins .
D12.776.377.715 Serum Globulins .
D12.776.377.715.548 Immunoglobulins .
D12.776.377.715.548.114 Antibodies .
D12.776.377.715.548.114.224 Antibodies, Monoclonal .
D12.776.377.715.548.114.224.200 Antibodies, Monoclonal, Humanized .
D12.776.377.715.548.114.224.200.782 Denosumab .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.374 Cytokines .
D12.776.467.374.750 Tumor Necrosis Factors .
D12.776.467.374.750.562 RANK Ligand .
D12.776.467.500 Ephrins .
D12.776.543 Membrane Proteins .
D12.776.543.287 Ephrins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.852 Receptors, Cytokine .
D12.776.543.750.705.852.760 Receptors, Tumor Necrosis Factor .
D12.776.543.750.705.852.760.245 Lymphotoxin beta Receptor .
D12.776.543.750.705.852.760.949 Tumor Necrosis Factor Decoy Receptors .
D12.776.543.750.705.852.760.949.249 Osteoprotegerin .
D23 Biological Factors .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.374 Cytokines .
D23.529.374.750 Tumor Necrosis Factors .
D23.529.374.750.562 RANK Ligand .
D23.529.500 Ephrins .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.265 Bradykinin Receptor Antagonists .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Osteoprotegerin .
FDCR-1 Protein .
Follicular Dendritic Cell-Derived Receptor-1 .
OCIF Protein .
Tumor Necrosis Factor Receptor 11b .
FDCR 1 Protein .
Follicular Dendritic Cell Derived Receptor 1 .
Osteoclastogenesis Inhibitory Factor .
Receptors, Tumor Necrosis Factor, Member 11b .
Tumor Necrosis Factor Receptor Superfamily, Member 11b .
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B. .
1.00
474035
 
Tumor Necrosis Factors .
TNF Receptor Ligands .
Tumor Necrosis Factor Superfamily Ligands .
Necrosis Factors, Tumor .
Receptor Ligands, TNF .
TNF 26382 .
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. .
0.46
482038
 
Denosumab .
AMG 162 .
Prolia .
Xgeva .
A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS. .
0.45
171052
 
Lymphotoxin beta Receptor .
Receptors, Lymphotoxin beta .
TNFR Superfamily, Member 3 .
Lymphotoxin beta Receptors .
Receptor, Lymphotoxin beta .
beta Receptor, Lymphotoxin .
beta Receptors, Lymphotoxin .
Tumor Necrosis Factor Receptor Superfamily, Member 3 .
A member of the tumor necrosis factor receptor superfamily. It has specificity for LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER and TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14. The receptor plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER T-CELLS. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. .
0.40
0403
 
RANK Ligand .
CD254 Antigen .
OPGL Protein .
Osteoclast Differentiation Factor .
Osteoprotegerin Ligand .
RANKL Protein .
Receptor Activator of Nuclear Factor-kappa B Ligand .
Receptor Activator of Nuclear Factor-kappaB Ligand .
TNF Superfamily, Member 11 .
TRANCE Protein .
Tumor Necrosis Factor-Related Activation-Induced Cytokine .
Antigen, CD254 .
Differentiation Factor, Osteoclast .
Receptor Activator of Nuclear Factor kappa B Ligand .
Receptor Activator of Nuclear Factor kappaB Ligand .
Tumor Necrosis Factor Related Activation Induced Cytokine .
Tumor Necrosis Factor Ligand Superfamily Member 11 .
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation. .
0.40
466222
 
Ephrins .
Eph Receptor Ligands .
Ligands, Eph Receptor .
Receptor Ligands, Eph .
Signaling proteins that are ligands for the EPH FAMILY RECEPTORS. They are membrane-bound proteins that are attached to the CELL MEMBRANE either through a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR or through a transmembrane domain. Many of the ephrins are considered important intercellular signaling molecules that control morphogenic changes during embryogenesis. .
0.39
1535
 
Bradykinin Receptor Antagonists .
Bradykinin Antagonists .
Bradykinin Receptor Blockers .
Bradykinin Receptor Inhibitors .
Antagonists, Bradykinin .
Antagonists, Bradykinin Receptor .
Inhibitors, Bradykinin Receptor .
Receptor Antagonists, Bradykinin .
Receptor Blockers, Bradykinin .
Receptor Inhibitors, Bradykinin .
Compounds and drugs that inhibit ligand binding or cellular signaling by BRADYKININ RECEPTORS. .
0.39
1786