serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.092 Amines .
D02.092.211 Biogenic Amines .
D02.092.211.215 Biogenic Monoamines .
D02.092.211.215.801 Tryptamines .
D02.092.211.215.801.852 Serotonin .
D03 Heterocyclic Compounds .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.473 Indoles .
D03.633.100.473.914 Tryptamines .
D03.633.100.473.914.814 Serotonin .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.870 Tryptophan Hydroxylase .
D12 Amino Acids, Peptides, and Proteins .
D12.125 Amino Acids .
D12.125.072 Amino Acids, Cyclic .
D12.125.072.050 Amino Acids, Aromatic .
D12.125.072.050.685 Phenylalanine .
D12.125.072.050.685.440 Fenclonine .
D12.125.072.050.850 Tryptophan .
D12.125.072.050.850.479 5-Hydroxytryptophan .
D23 Biological Factors .
D23.469 Inflammation Mediators .
D23.469.050 Autacoids .
D23.469.050.650 Serotonin .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Fenclonine .
CP-10,188 .
DL-3-(4-Chlorophenyl)alanine .
Fenclonin .
Fenclonine (L)-Isomer .
Fenclonine Hydrobromide .
Fenclonine Hydrochloride .
Fenclonine, (D)-Isomer .
Hydrobromide, Fenclonine .
Hydrochloride, Fenclonine .
para Chlorophenylalanine .
p-Chlorophenylalanine .
para-Chlorophenylalanine .
A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin. .
1.00
72564
 
Tryptophan Hydroxylase .
Hydroxylase, Tryptophan .
Monooxygenase, Tryptophan .
Tryptophan Monooxygenase .
An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN. .
0.51
102287
 
5-Hydroxytryptophan .
Hydroxytryptophan .
Oxitriptan .
Oxytryptophan .
Tryptophan, 5-Hydroxy- .
5 Hydroxytryptophan .
5-Hydroxy- Tryptophan .
Tryptophan, 5 Hydroxy .
5-HTP .
The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. .
0.44
53819
 
Serotonin .
3-(2-Aminoethyl)-1H-indol-5-ol .
Enteramine .
Hippophaine .
Hydroxytryptamine .
5 Hydroxytryptamine .
5-HT 13595 .
5-Hydroxytryptamine .
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator. .
0.44
34061596