serw-MX  [xml]  
 


    
 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.024 Adaptor Proteins, Signal Transducing .
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins .
D12.644.360.024.285.600 TNF Receptor-Associated Death Domain Protein .
D12.644.360.024.311 Myeloid Differentiation Factor 88 .
D12.644.360.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins .
D12.644.360.024.500.249 TNF Receptor-Associated Death Domain Protein .
D12.644.360.024.500.500 TNF Receptor-Associated Factor 1 .
D12.644.360.024.500.750 TNF Receptor-Associated Factor 2 .
D12.644.360.024.500.875 TNF Receptor-Associated Factor 3 .
D12.644.360.024.500.937 TNF Receptor-Associated Factor 5 .
D12.644.360.024.500.968 TNF Receptor-Associated Factor 6 .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.421 Death Domain Receptor Signaling Adaptor Proteins .
D12.644.360.075.421.600 TNF Receptor-Associated Death Domain Protein .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.057 Adaptor Proteins, Signal Transducing .
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.157.057.018.600 TNF Receptor-Associated Death Domain Protein .
D12.776.157.057.074 Myeloid Differentiation Factor 88 .
D12.776.157.057.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins .
D12.776.157.057.500.249 TNF Receptor-Associated Death Domain Protein .
D12.776.157.057.500.500 TNF Receptor-Associated Factor 1 .
D12.776.157.057.500.750 TNF Receptor-Associated Factor 2 .
D12.776.157.057.500.875 TNF Receptor-Associated Factor 3 .
D12.776.157.057.500.937 TNF Receptor-Associated Factor 5 .
D12.776.157.057.500.968 TNF Receptor-Associated Factor 6 .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.024 Adaptor Proteins, Signal Transducing .
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.476.024.320.775 TNF Receptor-Associated Death Domain Protein .
D12.776.476.024.390 Myeloid Differentiation Factor 88 .
D12.776.476.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins .
D12.776.476.024.500.249 TNF Receptor-Associated Death Domain Protein .
D12.776.476.024.500.500 TNF Receptor-Associated Factor 1 .
D12.776.476.024.500.750 TNF Receptor-Associated Factor 2 .
D12.776.476.024.500.875 TNF Receptor-Associated Factor 3 .
D12.776.476.024.500.937 TNF Receptor-Associated Factor 5 .
D12.776.476.024.500.968 TNF Receptor-Associated Factor 6 .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.421 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.476.075.421.600 TNF Receptor-Associated Death Domain Protein .
G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.820 Signal Transduction .
G04 Cell Physiological Phenomena .
G04.835 Signal Transduction .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
TNF Receptor-Associated Factor 5 .
TNF Receptor-Associated Protein 5 .
TRAF5 .
TNF Receptor Associated Factor 5 .
TNF Receptor Associated Protein 5 .
A signal transducing tumor necrosis factor receptor associated factor that mediates signaling from CD27 ANTIGENS; CD40 ANTIGENS; and the LYMPHOTOXIN BETA RECEPTOR. It is involved in regulation of NF-KAPPA B signaling. .
1.00
0100
 
TNF Receptor-Associated Factor 3 .
CD40 Receptor-Associated Factor 1 .
CD40bp Protein .
CRAF1 Protein .
LAP-1 Protein .
TRAF-3 .
TRAF3 .
CD40 Receptor Associated Factor 1 .
LAP 1 Protein .
TNF Receptor Associated Factor 3 .
A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation of NF-KAPPA B signaling and activation of MITOGEN-ACTIVATED PROTEIN KINASES. .
0.59
1388
 
TNF Receptor-Associated Factor 6 .
TRAF-6 Protein .
TRAF6 .
TNF Receptor Associated Factor 6 .
TRAF 6 Protein .
A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation of NF-KAPPA B signalling and activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES. .
0.55
01204
 
TNF Receptor-Associated Factor 2 .
LMP1-Associated Protein 1 .
TRAF2 .
LMP1 Associated Protein 1 .
TNF Receptor Associated Factor 2 .
A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPTOR feedback regulation. It is similar in structure and appears to work in conjunction with TNF RECEPTOR-ASSOCIATED FACTOR 1 to inhibit APOPTOSIS. .
0.48
0880
 
TNF Receptor-Associated Factor 1 .
TNF Receptor-Associated Protein 1 .
TRAF1 .
TNF Receptor Associated Factor 1 .
TNF Receptor Associated Protein 1 .
A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPTOR feedback regulation. It is similar in structure and appears to work in conjunction with TNF RECEPTOR-ASSOCIATED FACTOR 2 to inhibit APOPTOSIS. .
0.48
0436
 
TNF Receptor-Associated Death Domain Protein .
TRADD Protein .
TNF Receptor Associated Death Domain Protein .
A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex. .
0.45
0162
 
Myeloid Differentiation Factor 88 .
MyD88 Protein .
TLR Signal Adaptor Protein MyD88 .
Toll-Like Receptor Signal Adaptor Protein MyD88 .
Toll Like Receptor Signal Adaptor Protein MyD88 .
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES. .
0.43
33753
 
Signal Transduction .
Receptor Mediated Signal Transduction .
Signal Transduction Pathways .
Signal Transduction Systems .
Pathway, Signal .
Pathway, Signal Transduction .
Pathways, Signal .
Pathways, Signal Transduction .
Receptor-Mediated Signal Transductions .
Signal Pathway .
Signal Transduction Pathway .
Signal Transduction System .
Signal Transduction, Receptor-Mediated .
Signal Transductions .
Signal Transductions, Receptor-Mediated .
System, Signal Transduction .
Systems, Signal Transduction .
Transduction, Signal .
Transductions, Signal .
Receptor-Mediated Signal Transduction .
Signal Pathways .
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. .
0.43
464345469