Carcinogens. Initiators, Tumor . Promoters, Tumor . Oncogens . Tumor Initiators . Tumor Promoters . Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. . 0.44
Dimethylnitrosamine. N-Nitrosodimethylamine . NDMA Nitrosodimethylamine . N Nitrosodimethylamine . Nitrosodimethylamine, NDMA . Nitrosodimethylamine . A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents. . 0.41
Carcinogenesis. Oncogenesis . Carcinogeneses . Oncogeneses . Tumorigeneses . Tumorigenesis . The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. . 0.40
Carcinogenicity Tests. Carcinogen Tests . Carcinogenesis Tests . Carcinogenic Activity Tests . Carcinogenic Potency Tests . Carcinogen Test . Carcinogenesis Test . Carcinogenic Activity Test . Carcinogenic Potency Test . Carcinogenicity Test . Potency Test, Carcinogenic . Potency Tests, Carcinogenic . Test, Carcinogen . Test, Carcinogenesis . Test, Carcinogenic Activity . Test, Carcinogenic Potency . Test, Carcinogenicity . Test, Tumorigenicity . Tests, Carcinogen . Tests, Carcinogenesis . Tests, Carcinogenic Activity . Tests, Carcinogenic Potency . Tests, Carcinogenicity . Tests, Tumorigenicity . Tumorigenicity Test . Tumorigenicity Tests . Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values. . 0.38