serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.464 Ligases .
D08.811.464.938 Ubiquitin-Protein Ligase Complexes .
D08.811.464.938.750 Ubiquitin-Protein Ligases .
D08.811.464.938.750.210 Inhibitor of Apoptosis Proteins .
D08.811.464.938.750.210.250 Baculoviral IAP Repeat-Containing 3 Protein .
D08.811.913 Transferases .
D08.811.913.696 Phosphotransferases .
D08.811.913.696.445 Nucleotidyltransferases .
D08.811.913.696.445.735 RNA Nucleotidyltransferases .
D08.811.913.696.445.735.720 RNA Helicases .
D08.811.913.696.445.735.720.249 DEAD-box RNA Helicases .
D08.811.913.696.445.735.720.249.875 Interferon-Induced Helicase, IFIH1 .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.128 Circadian Rhythm Signaling Peptides and Proteins .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.335 Beclin-1 .
D12.644.360.075.437 Inhibitor of Apoptosis Proteins .
D12.644.360.075.437.250 Baculoviral IAP Repeat-Containing 3 Protein .
D12.644.360.650 RNA-Binding Protein EWS .
D12.776 Proteins .
D12.776.094 Autophagy-Related Proteins .
D12.776.094.500 Beclin-1 .
D12.776.124 Blood Proteins .
D12.776.124.486 Immunoproteins .
D12.776.124.486.485 Immunoglobulins .
D12.776.124.486.485.114 Antibodies .
D12.776.124.486.485.114.323 Autoantibodies .
D12.776.124.486.485.114.323.210 Antibodies, Antiphospholipid .
D12.776.124.486.485.114.323.210.600 Lupus Coagulation Inhibitor .
D12.776.124.790 Serum Globulins .
D12.776.124.790.651 Immunoglobulins .
D12.776.124.790.651.114 Antibodies .
D12.776.124.790.651.114.323 Autoantibodies .
D12.776.124.790.651.114.323.210 Antibodies, Antiphospholipid .
D12.776.124.790.651.114.323.210.600 Lupus Coagulation Inhibitor .
D12.776.157 Carrier Proteins .
D12.776.157.142 Calmodulin-Binding Proteins .
D12.776.157.142.750 RNA-Binding Protein EWS .
D12.776.157.725 RNA-Binding Proteins .
D12.776.157.725.813 RNA Recognition Motif Proteins .
D12.776.157.725.813.750 Heterogeneous-Nuclear Ribonucleoproteins .
D12.776.157.725.813.750.900 RNA-Binding Protein EWS .
D12.776.189 Circadian Rhythm Signaling Peptides and Proteins .
D12.776.220 Cytoskeletal Proteins .
D12.776.220.909 Pyrin .
D12.776.260 DNA-Binding Proteins .
D12.776.260.645 Paired Box Transcription Factors .
D12.776.260.645.813 PAX6 Transcription Factor .
D12.776.377 Globulins .
D12.776.377.715 Serum Globulins .
D12.776.377.715.548 Immunoglobulins .
D12.776.377.715.548.114 Antibodies .
D12.776.377.715.548.114.323 Autoantibodies .
D12.776.377.715.548.114.323.210 Antibodies, Antiphospholipid .
D12.776.377.715.548.114.323.210.600 Lupus Coagulation Inhibitor .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.335 Beclin-1 .
D12.776.476.075.437 Inhibitor of Apoptosis Proteins .
D12.776.476.075.437.250 Baculoviral IAP Repeat-Containing 3 Protein .
D12.776.476.650 RNA-Binding Protein EWS .
D12.776.624 Neoplasm Proteins .
D12.776.624.664 Oncogene Proteins .
D12.776.624.664.700 Proto-Oncogene Proteins .
D12.776.624.664.700.913 RNA-Binding Protein EWS .
D12.776.631 Nerve Tissue Proteins .
D12.776.631.249 Dopamine and cAMP-Regulated Phosphoprotein 32 .
D12.776.664 Nucleoproteins .
D12.776.664.962 RNA-Binding Proteins .
D12.776.664.962.813 RNA Recognition Motif Proteins .
D12.776.664.962.813.750 Heterogeneous-Nuclear Ribonucleoproteins .
D12.776.664.962.813.750.900 RNA-Binding Protein EWS .
D12.776.744 Phosphoproteins .
D12.776.744.459 Dopamine and cAMP-Regulated Phosphoprotein 32 .
D12.776.930 Transcription Factors .
D12.776.930.700 Paired Box Transcription Factors .
D12.776.930.700.813 PAX6 Transcription Factor .
D12.776.934 Tripartite Motif Proteins .
D12.776.934.750 Pyrin .
D23 Biological Factors .
D23.113 Blood Coagulation Factor Inhibitors .
D23.113.475 Lupus Coagulation Inhibitor .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Pyrin .
MEFV Protein .
Marenostrin .
Mediterranean Fever Protein .
TRIM20 Protein .
A tripartite motif protein that consists of an N-terminal pyrin domain, a central coiled-coil region and B-box type ZINC FINGER, and C-terminal regions that mediate homotrimerization and interactions with other proteins (the B30.2/SPRY DOMAIN). It is expressed primarily by mature GRANULOCYTES and associates with the cytoskeleton in the perinuclear area as well as AUTOPHAGOSOMES, where it co-ordinates the assembly of AUTOPHAGY-RELATED PROTEINS and degradation of INFLAMMASOME components. It functions in INNATE IMMUNITY and INFLAMMATION; mutations in the Pyrin protein (MEFV) gene are associated with FAMILIAL MEDITERRANEAN FEVER. .
1.00
1763
 
Baculoviral IAP Repeat-Containing 3 Protein .
Apoptosis Inhibitor 2 .
BIRC3 Protein .
Baculoviral IAP Repeat Containing Protein 3 .
Cellular Inhibitor of Apoptosis-2 .
Hiap-1 Protein .
IAP1 Protein .
Inhibitor of Apoptosis 1 Protein .
Inhibitor of Apoptosis Protein 1 .
c-IAP2 Protein .
cIAP2 Protein .
Apoptosis-2 Cellular Inhibitor .
Baculoviral IAP Repeat Containing 3 Protein .
Cellular Inhibitor of Apoptosis 2 .
Hiap 1 Protein .
Inhibitor 2, Apoptosis .
A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells. .
0.39
0263
 
Dopamine and cAMP-Regulated Phosphoprotein 32 .
DARPP-32 Protein .
Dopamine and Adenosine 3',5'-Monophosphate-Regulated Phosphoprotein .
Dopamine and cAMP-Regulated Phosphoprotein .
Dopamine- and Cyclic AMP-Regulated Phosphoprotein Mr 32,000 .
DARPP 32 Protein .
Dopamine and Adenosine 3',5' Monophosphate Regulated Phosphoprotein .
Dopamine and Cyclic AMP Regulated Phosphoprotein Mr 32,000 .
Dopamine and cAMP Regulated Phosphoprotein .
Dopamine and cAMP Regulated Phosphoprotein 32 .
A phosphoprotein that was initially identified as a major target of DOPAMINE activated ADENYLYL CYCLASE in the CORPUS STRIATUM. It regulates the activities of PROTEIN PHOSPHATASE-1 and PROTEIN KINASE A, and it is a key mediator of the biochemical, electrophysiological, transcriptional, and behavioral effects of DOPAMINE. .
0.37
0825
 
Beclin-1 .
ATG-6 Protein .
ATG6 Protein .
Beclin-1 Protein .
Beclin1 .
Coiled-coil Myosin-like Bcl2-interacting Protein .
GT197 Protein .
ATG 6 Protein .
Beclin 1 .
Beclin 1 Protein .
Coiled coil Myosin like Bcl2 interacting Protein .
An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN. .
0.37
01745
 
Circadian Rhythm Signaling Peptides and Proteins .
Circadian Rhythm Signaling Peptides .
Circadian Rhythm Signaling Proteins .
Circadian Clock Proteins and Peptides .
A broad category of proteins that regulate the CIRCADIAN RHYTHM of an organism. Included here are proteins that transmit intracellular and intercellular signals in a chronological manner along with proteins that sense light and time-dependent changes in the environment such as the PHOTOPERIOD. .
0.36
 
PAX6 Transcription Factor .
Aniridia Type II Protein .
Oculorhombin .
PAX6 Protein .
Paired Box Gene 6 Protein .
Paired Box Protein Pax-6 .
Paired Box Transcription Factor 6 .
Pax-6 Protein .
Pax6.1 Protein .
Pax6.2 Protein .
Transcription Factor PAX6 .
Factor PAX6, Transcription .
Factor, PAX6 Transcription .
PAX6, Transcription Factor .
Paired Box Protein Pax 6 .
Pax 6 Protein .
Protein, PAX6 .
Protein, Pax-6 .
Protein, Pax6.1 .
Protein, Pax6.2 .
Transcription Factor, PAX6 .
A paired box transcription factor that has important functions in the development of the eye, nose, central nervous system and pancreas. Mutations in the PAX6 gene are associated with ocular disorders such as ANIRIDIA. .
0.36
01708
 
Lupus Coagulation Inhibitor .
Anticoagulant, Lupus .
Coagulation Inhibitor, Lupus .
Inhibitor, Lupus Coagulation .
Lupus Anticoagulant .
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications. .
0.36
702685
 
Tripartite Motif Proteins .
RBCC Protein Family .
RBCC Proteins .
TRIM Protein Family .
TRIM Proteins .
Family, RBCC Protein .
Family, TRIM Protein .
Motif Proteins, Tripartite .
Protein Family, RBCC .
Protein Family, TRIM .
Proteins, RBCC .
Proteins, TRIM .
Proteins, Tripartite Motif .
A protein family defined by the presence of three ZINC FINGER domains, one of which is a RING FINGER DOMAIN, a coiled-coil region, and a highly variable C-terminal region. They function in many cellular processes including APOPTOSIS and CELL CYCLE regulation. .
0.36
1728
 
Interferon-Induced Helicase, IFIH1 .
CADM-140 Autoantigen .
Helicard .
IFIH1 Protein .
Interferon Induced with Helicase C Domain 1 .
Interferon-Induced Helicase C Domain-Containing Protein 1 .
Melanoma Differentiation-Associated Protein 5 .
Autoantigen, CADM-140 .
CADM 140 Autoantigen .
Helicase, IFIH1 Interferon-Induced .
IFIH1 Interferon-Induced Helicase .
Interferon Induced Helicase C Domain Containing Protein 1 .
Interferon Induced Helicase, IFIH1 .
Melanoma Differentiation Associated Protein 5 .
A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS. .
0.35
0555
 
RNA-Binding Protein EWS .
EWS Protein .
EWS Proto-Oncogene Protein .
EWS RNA Binding Protein 1 .
EWSR1 Protein .
Ewing Sarcoma Breakpoint Region 1 Protein .
Ewing Sarcoma Breakpointregion 1 Protein .
EWS Proto Oncogene Protein .
EWS, RNA-Binding Protein .
Protein, EWSR1 .
Proto-Oncogene Protein, EWS .
RNA Binding Protein EWS .
A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA. .
0.35
0903