Fertilins. ADAM 1a Protein . ADAM 2 Protein . ADAM1 Protein . ADAM1a Protein . ADAM2 Protein . Fertilin . Fertilin Protein . Fertilin alpha . Fertilin beta . PH 30 Fusion Protein . PH-30 Fusion Protein . PH-30 Protein . PH-30 alpha . PH-30 beta . PH 30 Protein . PH 30 alpha . PH 30 beta . alpha, Fertilin . alpha, PH-30 . beta, Fertilin . beta, PH-30 . Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity. . 1.00
ADAM Proteins. A Disintegrin and Metalloprotease Proteins . ADAM (A Disintegrin and Metalloprotease) Proteins . A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain. . 0.87
ADAM12 Protein. ADAM 12 Protein . ADAM-12 Protein . ADAM12-L Protein . ADAM12-S Protein . Disintegrin and Metalloproteinase Domain-Containing Protein 12 . Meltrin-alpha Protein . ADAM12 L Protein . ADAM12 S Protein . Disintegrin and Metalloproteinase Domain Containing Protein 12 . Meltrin alpha Protein . A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS. . 0.76
ADAMTS Proteins. A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins . ADAMTS Proteases . ADAMTS-Like Proteins . ADAMTSL Proteins . Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins . ADAMTS Like Proteins . A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX. . 0.76
ADAM10 Protein. ADAM-10 Protein . CD156c Antigen . CD156w Antigen . Disintegrin and Metalloproteinase Domain-Containing Protein 10 . ADAM 10 Protein . Antigen, CD156c . Antigen, CD156w . Disintegrin and Metalloproteinase Domain Containing Protein 10 . A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE 76 and VALINE 77 to its functional form, as well as several other CELL SURFACE PROTEINS to their soluble forms, including AMYLOID BETA-PROTEIN PRECURSOR and PRION PROTEIN. . 0.75
ADAM17 Protein. ADAM-17 . ADAM-17 Protein . CD156b Antigen . Disintegrin and Metalloproteinase Domain-Containing Protein 17 . TACA (Enzyme) . TACE (Enzyme) . TNF-alpha Convertase . TNF-alpha Converting Enzyme . Tumor Necrosis Factor Alpha Convertase . Tumor Necrosis Factor-alpha Convertase . Tumor Necrosis Factor-alpha Converting Enzyme . ADAM 17 Protein . Antigen, CD156b . Convertase, TNF-alpha . Disintegrin and Metalloproteinase Domain Containing Protein 17 . TNF alpha Convertase . TNF alpha Converting Enzyme . Tumor Necrosis Factor alpha Converting Enzyme . A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS. . 0.75
ADAMTS1 Protein. A Disintegrin And Metalloproteinase with Thrombospondin Motifs 1 Protein . ADAMTS-1 Protein . ADAMTS1 Protease . ADAMTS 1 Protein . An ADAMTS protease that contains two disintegrin loops and three C-terminal thrombospondin (TS) motifs. It functions as an ANGIOGENESIS INHIBITOR as well as in normal tissue growth and fertility. . 0.73
ADAMTS5 Protein. A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein . ADAMTS-5 Protein . ADAMTS11 Protein . ADAMTS5 Protease . Aggrecanase-2 . ADAMTS 5 Protein . Aggrecanase 2 . An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE, and may be involved in the destruction of aggrecan in ARTHRITIS. . 0.72