serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.241 Carboxylic Acids .
D02.241.081 Acids, Acyclic .
D02.241.081.114 Butyrates .
D02.241.081.114.500 Aminobutyrates .
D02.241.081.114.500.350 gamma-Aminobutyric Acid .
D12 Amino Acids, Peptides, and Proteins .
D12.125 Amino Acids .
D12.125.190 Aminobutyrates .
D12.125.190.350 gamma-Aminobutyric Acid .
D12.776 Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.720 Receptors, Neurotransmitter .
D12.776.543.750.720.200 Receptors, Amino Acid .
D12.776.543.750.720.200.300 Receptors, GABA .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.625 Neurotransmitter Agents .
D27.505.519.625.240 GABA Agents .
D27.505.519.625.240.500 GABA Modulators .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.577 Neurotransmitter Agents .
D27.505.696.577.240 GABA Agents .
D27.505.696.577.240.500 GABA Modulators .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
GABA Modulators .
GABAergic Modulators .
Acid Modulators, gamma-Aminobutyric .
Modulators, GABA .
Modulators, GABAergic .
Modulators, gamma-Aminobutyric Acid .
gamma Aminobutyric Acid Modulators .
gamma-Aminobutyric Acid Modulators .
Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here. .
1.00
112705
 
gamma-Aminobutyric Acid .
4-Aminobutanoic Acid .
Aminalon .
Aminalone .
Gammalon .
Lithium GABA .
gamma-Aminobutyric Acid, Calcium Salt (2:1) .
gamma-Aminobutyric Acid, Hydrochloride .
gamma-Aminobutyric Acid, Monolithium Salt .
gamma-Aminobutyric Acid, Monosodium Salt .
gamma-Aminobutyric Acid, Zinc Salt (2:1) .
4 Aminobutanoic Acid .
4 Aminobutyric Acid .
Acid, Hydrochloride gamma-Aminobutyric .
GABA, Lithium .
Hydrochloride gamma-Aminobutyric Acid .
gamma Aminobutyric Acid .
gamma Aminobutyric Acid, Hydrochloride .
gamma Aminobutyric Acid, Monolithium Salt .
gamma Aminobutyric Acid, Monosodium Salt .
4-Aminobutyric Acid .
GABA 4414 .
The most common inhibitory neurotransmitter in the central nervous system. .
0.81
14235760
 
Receptors, GABA .
GABA Receptor .
gamma-Aminobutyric Acid Receptor .
Receptor, GABA .
Receptor, gamma-Aminobutyric Acid .
Receptors, gamma Aminobutyric Acid .
gamma Aminobutyric Acid Receptor .
gamma Aminobutyric Acid Receptors .
gamma-Aminobutyric Acid Receptors .
GABA Receptors .
Receptors, gamma-Aminobutyric Acid .
Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen. .
0.75
233484