serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.241 Carboxylic Acids .
D02.241.081 Acids, Acyclic .
D02.241.081.337 Dicarboxylic Acids .
D02.241.081.337.351 Glutarates .
D02.241.081.337.351.550 Meglutol .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.047 Alcohol Oxidoreductases .
D08.811.682.047.820 NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases .
D08.811.682.047.820.150 3-Hydroxyacyl CoA Dehydrogenases .
D08.811.682.047.820.150.415 Hydroxymethylglutaryl CoA Reductases .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Meglutol .
3-Hydroxy-3-methylpentanedioic Acid .
beta-Hydroxy-beta-Methylglutarate .
3 Hydroxy 3 methylglutaric Acid .
3 Hydroxy 3 methylpentanedioic Acid .
Acid, 3-Hydroxy-3-methylglutaric .
Acid, 3-Hydroxy-3-methylpentanedioic .
beta Hydroxy beta Methylglutarate .
3-Hydroxy-3-methylglutaric Acid .
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol. .
1.00
 
Hydroxymethylglutaryl CoA Reductases .
3-Hydroxy-3-methylglutaryl CoA Reductase .
HMG CoA Reductase .
Hydroxymethylglutaryl CoA Reductase .
3 Hydroxy 3 methylglutaryl CoA Reductase .
CoA Reductase, 3-Hydroxy-3-methylglutaryl .
Reductase, 3-Hydroxy-3-methylglutaryl CoA .
HMG CoA Reductases .
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID. .
0.74