Dactinomycin. Cosmegen . Cosmegen Lyovac . Lyovac-Cosmegen . Lyovac Cosmegen . Lyovac, Cosmegen . LyovacCosmegen . Actinomycin D . Meractinomycin . Actinomycin . A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) . 1.00
Actinomyces. A genus of gram-positive, rod-shaped bacteria whose organisms are nonmotile. Filaments that may be present in certain species are either straight or wavy and may have swollen or clubbed heads. . 0.65
Actinomycosis. Infections, Actinomyces . Actinomyces Infection . Actinomycoses . Infection, Actinomyces . Actinomyces Infections . Infections with bacteria of the genus ACTINOMYCES. . 0.60
Actinobacteria. High G+C Gram-Positive Bacteria . Actinomycetes . Gram-Positive Bacteria, High G+C . ACTINOBACTERIA GROUP . Class of BACTERIA with diverse morphological properties. Strains of Actinobacteria show greater than 80% 16S rDNA/rRNA sequence similarity among each other and also the presence of certain signature nucleotides. (Stackebrandt E. et al, Int. J. Syst. Bacteriol. (1997) 47:479-491) . 0.59
Mycetoma. Actinomycetoma . Eumycetoma . Actinomycetomas . Eumycetomas . Foot, Madura . Maduromycoses . Mycetomas . Madura Foot . Maduromycosis . A chronic progressive subcutaneous infection caused by species of fungi (eumycetoma), or actinomycetes (actinomycetoma). It is characterized by tumefaction, abscesses, and tumor-like granules representing microcolonies of pathogens, such as MADURELLA fungi and bacteria ACTINOMYCETES, with different grain colors. . 0.57
Actinomycetales. Corynebacteriaceae . Coryneform Group . Nocardioform Group . An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments. . 0.56