Alarmins. Alarmin . Alarmin Proteins . Damage-Associated Molecular Pattern Molecules . Danger-Associated Molecular Pattern Molecules . Damage Associated Molecular Pattern Molecules . Danger Associated Molecular Pattern Molecules . A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis. . 1.00
Alarm. Signal giving warning of danger (Material II - IDNDR, 1992) . 0.69
Proteins. Protein Gene Products . Proteins, Gene . Gene Proteins . Gene Products, Protein . GENE PRODUCTS . Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. . 0.60
Jagged-1 Protein. Alagille Syndrome Protein . CD339 Antigen . Jagged-1 . Jagged1 Protein . Serrate-1 Protein . Serrate1 Protein . Antigen, CD339 . Jagged 1 . Jagged 1 Protein . Serrate 1 Protein . A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1. . 0.52
Apolipoproteins L. ApoL Proteins . Apolipoprotein L Family . A family of apolipoproteins occurring in humans that are structurally similar to B-CELL LEUKEMIA 2 FAMILY PROTEINS. In addition to their roles in cholesterol and lipid transport, they are expressed by MYELOID CELLS and ENDOTHELIAL CELLS during INFLAMMATION and may function to promote CELL DEATH. . 0.48
ADAM Proteins. A Disintegrin and Metalloprotease Proteins . ADAM (A Disintegrin and Metalloprotease) Proteins . A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain. . 0.47
Alanine. Abufène . Alanine, L-Isomer . L-Alanine . Alanine, L Isomer . L Alanine . L-Isomer Alanine . A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM. . 0.47
Receptor for Advanced Glycation End Products. AGE Receptor . AGER Protein . Advanced Glycosylation End Product Receptors . Advanced Glycosylation End Product-Specific Receptor . Advanced Glycosylation End-Product Receptor . Advanced Glycosylation End-Product Receptors . Advanced Glycosylation Endproduct Receptors . Amphoterin Receptor . RAGE (Receptor for Advanced Glycation End Products) . Receptor for Advanced Glycation End Products (RAGE) . Receptor for Advanced Glycation Endproducts . Receptor, Advanced Glycosylation End-Product . Receptor, Advanced Glycosylation End-Products . Advanced Glycosylation End Product Receptor . Advanced Glycosylation End Product Specific Receptor . Protein, AGER . Receptor, AGE . Receptor, Advanced Glycosylation End Product . Receptor, Advanced Glycosylation End Products . Receptor, Amphoterin . A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED GLYCATION END PRODUCTS to mediate cellular responses to both acute and chronic vascular inflammation in conditions such as ATHEROSCLEROSIS and DIABETES MELLITUS, TYPE 2. It also binds AMYLOID BETA PEPTIDES and the ALARMINS - S100A12 and S100 CALCIUM BINDING PROTEIN BETA SUBUNIT. . 0.46
