Capsaicin. 8-Methyl-N-Vanillyl-6-Nonenamide . Antiphlogistine Rub A-535 Capsaicin . Axsain . Capsaicine . Capsicum Farmaya . Capsidol . Capsin . Capzasin . Gelcen . Katrum . NGX-4010 . Zacin . Zostrix . 8 Methyl N Vanillyl 6 Nonenamide . NGX 4010 . NGX4010 . An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS. . 1.00
TRPV Cation Channels. Capsaicin Receptors . Vanilloid Receptors . Cation Channels, TRPV . Channels, TRPV Cation . Receptors, Capsaicin . Receptors, Vanilloid . A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold. . 0.56
Transient Receptor Potential Channels. TRP Cation Channels . TRP Membrane Proteins . Transient Receptor Potential Cation Channels . Cation Channels, TRP . Channels, TRP Cation . Membrane Proteins, TRP . Proteins, TRP Membrane . TRP Cation Channels . TRP Membrane Proteins . A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES. . 0.53
TRPC Cation Channels. Transient Receptor Potential Cation Channel Subfamily C . Transient Receptor Potential Channels, Type C . Cation Channels, TRPC . Channels, TRPC Cation . A subgroup of TRP cation channels that contain 3-4 ANKYRIN REPEAT DOMAINS and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10. . 0.51
TRPP Cation Channels. Polycystins . Cation Channels, TRPP . Channels, TRPP Cation . A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are associated with POLYCYSTIC KIDNEY DISEASES. . 0.51