serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.033 Alcohols .
D02.033.100 Amino Alcohols .
D02.033.100.624 Propanolamines .
D02.033.100.624.915 Timolol .
D02.033.755 Propanols .
D02.033.755.624 Propanolamines .
D02.033.755.624.915 Timolol .
D02.033.800 Sugar Alcohols .
D02.033.800.400 Galactitol .
D02.033.800.400.350 Dianhydrogalactitol .
D02.092 Amines .
D02.092.063 Amino Alcohols .
D02.092.063.624 Propanolamines .
D02.092.063.624.915 Timolol .
D02.092.877 Quaternary Ammonium Compounds .
D02.092.877.096 Benzylammonium Compounds .
D02.092.877.096.333 Bretylium Compounds .
D02.092.877.096.333.150 Bretylium Tosylate .
D02.092.877.883 Trimethyl Ammonium Compounds .
D02.092.877.883.333 Choline .
D02.092.877.883.333.720 Propylbenzilylcholine Mustard .
D02.455 Hydrocarbons .
D02.455.526 Hydrocarbons, Halogenated .
D02.455.526.728 Mustard Compounds .
D02.455.526.728.650 Nitrogen Mustard Compounds .
D02.455.526.728.650.594 Melphalan .
D02.455.526.728.650.594.690 Peptichemio .
D02.455.526.728.650.740 Propylbenzilylcholine Mustard .
D02.675 Onium Compounds .
D02.675.276 Quaternary Ammonium Compounds .
D02.675.276.232 Choline .
D02.675.276.232.720 Propylbenzilylcholine Mustard .
D02.886 Sulfur Compounds .
D02.886.675 Thiazoles .
D02.886.675.867 Thiadiazoles .
D02.886.675.867.768 Timolol .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.129 Azoles .
D03.383.129.708 Thiazoles .
D03.383.129.708.867 Thiadiazoles .
D03.383.129.708.867.768 Timolol .
D03.383.533 Oxazines .
D03.383.533.640 Morpholines .
D03.383.533.640.775 Timolol .
D09 Carbohydrates .
D09.853 Sugar Alcohols .
D09.853.400 Galactitol .
D09.853.400.350 Dianhydrogalactitol .
D12 Amino Acids, Peptides, and Proteins .
D12.125 Amino Acids .
D12.125.072 Amino Acids, Cyclic .
D12.125.072.050 Amino Acids, Aromatic .
D12.125.072.050.685 Phenylalanine .
D12.125.072.050.685.500 Melphalan .
D12.644 Peptides .
D12.644.456 Oligopeptides .
D12.644.456.726 Peptichemio .
D12.776 Proteins .
D12.776.624 Neoplasm Proteins .
D12.776.624.301 Melanoma-Specific Antigens .
D12.776.624.301.750 MART-1 Antigen .
D23 Biological Factors .
D23.050 Antigens .
D23.050.285 Antigens, Neoplasm .
D23.050.285.439 Melanoma-Specific Antigens .
D23.050.285.439.750 MART-1 Antigen .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Melphalan .
4-(Bis(2-chloroethyl)amino)phenylalanine .
Alkeran .
L-PAM .
Mustard, Phenylalanine .
Medphalan .
Merphalan .
Phenylalanine Mustard .
Sarcolysine .
Sarkolysin .
An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. .
1.00
266876
 
Peptichemio .
A mixture of six synthetic oligopeptides, each containing MELPHALAN. It is used as a broad-spectrum antineoplastic due to its alkylating and antimetabolic actions but, is toxic to bone marrow, gastrointestinal system and vasculature. .
0.36
0186
 
Timolol .
(S)-1-((1,1-Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol .
Blocadren .
L-714,465 .
MK-950 .
Optimol .
Timacar .
Timolol Hemihydrate .
Timolol Maleate .
Timolol Maleate, (1:1) Salt .
Timoptic .
Timoptol .
Hemihydrate, Timolol .
L 714,465 .
L714,465 .
MK 950 .
MK950 .
A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor. .
0.35
733469
 
MART-1 Antigen .
MART1 Antigen .
Melan-A .
MelanA .
Antigen, MART-1 .
Antigen, MART1 .
Antigens, MART1 .
MART 1 Antigen .
Melan A .
Melanoma Antigen Recognized by T Cells 1 .
MART1 Antigens .
Melanoma Antigen Recognized by T-Cells 1 .
A melanosome-specific protein that plays a role in the expression, stability, trafficking, and processing of GP100 MELANOMA ANTIGEN, which is critical to the formation of Stage II MELANOSOMES. The protein is used as an antigen marker for MELANOMA cells. .
0.35
21085
 
Nitrogen Mustard Compounds .
Compounds, Nitrogen Mustard .
Mustard Compounds, Nitrogen .
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. .
0.34
02859
 
Propylbenzilylcholine Mustard .
PRBCM .
Mustard, Propylbenzilylcholine .
An analog of benzilylcholine mustard. It is an alkylating nitrogen mustard analog that binds specifically and irreversibly to cholinergic muscarinic receptors and is used as an affinity label to isolate and study the receptors. .
0.32
0108
 
Dianhydrogalactitol .
1,2,5,6-Dianhydrogalactitol .
NSC-132313 .
NSC 132313 .
NSC132313 .
Dianhydrodulcitol .
Diepoxydulcitol .
Diepoxygalactitol .
One of the cytotoxic dihalohexitols that may have alkylating antineoplastic activity. It causes bone marrow toxicity. The active form is thought to be the diepoxide. .
0.32
0112
 
Bretylium Tosylate .
Bretylate .
Bretylium Tosilate .
Bretylol .
Ornid .
An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now proposed as an anti-arrhythmic. .
0.32
4262