Phenytoin. 5,5-Diphenylhydantoin . 5,5-diphenylimidazolidine-2,4-dione . Antisacer . Difenin . Dihydan . Dilantin . Epamin . Epanutin . Hydantol . Phenytoin Sodium . Sodium Diphenylhydantoinate . Diphenylhydantoinate, Sodium . Diphenylhydantoin . Fenitoin . An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. . 1.00
Flavoxate. Bladuril . Flavoxate Hydrochloride . Spasuret . Urispas . Uronid . Hydrochloride, Flavoxate . A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. . 0.44
Zoxazolamine. A uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood. . 0.42
Apomorphine. Apokinon . Apomorphin-Teclapharm . Apomorphine Chloride . Apomorphine Hydrochloride . Apomorphine Hydrochloride Anhydrous . Apomorphine Hydrochloride, Anhydrous . Apomorphine Hydrochloride, Hemihydrate . Britaject . Anhydrous Apomorphine Hydrochloride . Anhydrous, Apomorphine Hydrochloride . Apomorphin Teclapharm . ApomorphinTeclapharm . Chloride, Apomorphine . Hemihydrate Apomorphine Hydrochloride . Hydrochloride Anhydrous, Apomorphine . Hydrochloride, Anhydrous Apomorphine . Hydrochloride, Apomorphine . Hydrochloride, Hemihydrate Apomorphine . A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use. . 0.42
Heptaminol. Cardiomax . Heptaminol Hydrochloride . An amino alcohol that has been used as a myocardial stimulant and vasodilator and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. The mechanism of heptaminol's therapeutic actions is not well understood although it has been suggested to affect catecholamine release or calcium metabolism. . 0.41
Dantrolene. Dantrium . Dantrolene Sodium . Sodium, Dantrolene . Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants. . 0.40
Succinylcholine. Anectine . Celocurine . Ditilin . Listenon . Lysthenon . Myorelaxin . Quelicin . Succicuran . Succinylcholine Chloride . Succinylcholine Dibromide . Succinylcholine Dichloride . Succinylcholine Dichloride, Di-H2O . Succinylcholine Diiodide . Succinylcholine Diperchlorate . Succinylcholine Iodide . Suxamethonium Bromide . Suxamethonium Chloride . Bromide, Suxamethonium . Dibromide, Succinylcholine . Dichloride, Succinylcholine . Diiodide, Succinylcholine . Diperchlorate, Succinylcholine . Succinylcholine Dichloride, Di H2O . Succinyldicholine . Suxamethonium . A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for. . 0.40
Nicardipine. Antagonil . Cardene . Cardene I.V. . Cardene SR . Dagan . Flusemide . Lecibral . Lincil . Loxen . Lucenfal . Nicardipine Hydrochloride . Nicardipine LA . Nicardipino Ratiopharm . Nicardipino Seid . Perdipine . Ridene . Vasonase . Y-93 13127 . Hydrochloride, Nicardipine . LA, Nicardipine . Y 93 13127 . Y93 13127 . A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. . 0.39
Pyridostigmine Bromide. Mestinon . Pyridostigmine . Bromide, Pyridostigmine . A cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants. . 0.39
Quinine. Biquinate . Legatrim . Myoquin . Quinamm . Quinbisan . Quinbisul . Quindan . Quinimax . Quinine Bisulfate . Quinine Hydrochloride . Quinine Lafran . Quinine Sulfate . Quinine Sulphate . Quinine-Odan . Quinoctal . Quinson . Quinsul . Strema . Surquina . Bisulfate, Quinine . Hydrochloride, Quinine . Sulfate, Quinine . Sulphate, Quinine . An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood. . 0.39