Guanethidine. ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine . Guanethidine Monosulfate . Guanethidine Sulfate . Guanethidine Sulfate (1:1) . Guanethidine Sulfate (1:2) . Guanethidine Sulfate (2:1) . Guanethidine Sulfate (2:1), 14C-Labeled . Ismelin . Isobarin . Octadine . Oktadin . Monosulfate, Guanethidine . Sulfate, Guanethidine . An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. . 1.00
Norepinephrine. Arterenol . Levonor . Levophed . Levophed Bitartrate . Noradrenaline Bitartrate . Noradrénaline tartrate renaudin . Norepinephrin d-Tartrate (1:1) . Norepinephrine Bitartrate . Norepinephrine Hydrochloride . Norepinephrine Hydrochloride, (+)-Isomer . Norepinephrine Hydrochloride, (+,-)-Isomer . Norepinephrine d-Tartrate (1:1) . Norepinephrine l-Tartrate (1:1) . Norepinephrine l-Tartrate (1:1), (+,-)-Isomer . Norepinephrine l-Tartrate (1:1), Monohydrate . Norepinephrine l-Tartrate (1:1), Monohydrate, (+)-Isomer . Norepinephrine l-Tartrate (1:2) . Norepinephrine l-Tartrate, (+)-Isomer . Norepinephrine, (+)-Isomer . Norepinephrine, (+,-)-Isomer . Bitartrate, Levophed . Bitartrate, Noradrenaline . Bitartrate, Norepinephrine . Hydrochloride, Norepinephrine . renaudin, Noradrénaline tartrate . tartrate renaudin, Noradrénaline . Levarterenol . Levonorepinephrine . Noradrenaline . Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic. . 0.47
Adrenal Medulla. Adrenal Medullas . Medulla, Adrenal . Medullas, Adrenal . The inner portion of the adrenal gland. Derived from ECTODERM, adrenal medulla consists mainly of CHROMAFFIN CELLS that produces and stores a number of NEUROTRANSMITTERS, mainly adrenaline (EPINEPHRINE) and NOREPINEPHRINE. The activity of the adrenal medulla is regulated by the SYMPATHETIC NERVOUS SYSTEM. . 0.40
Norepinephrine Plasma Membrane Transport Proteins. NET Protein, Neuronal . Noradrenaline Plasma Membrane Transport Proteins . Noradrenaline Transporter . Norepinephrine Transporter . Norepinephrine Transporter Protein . SLC6A2 Protein . Sodium-Dependent Noradrenaline Transporter . Solute Carrier Family 6 Member 2 . Neuronal NET Protein . Neurotransmitter Transporters, Noradrenaline Specific . Noradrenaline Transporter, Sodium-Dependent . Noradrenaline-Specific Neurotransmitter Transporters . Sodium Dependent Noradrenaline Transporter . Transporter Protein, Norepinephrine . Transporter, Noradrenaline . Transporter, Norepinephrine . Transporters, Noradrenaline-Specific Neurotransmitter . Neurotransmitter Transporters, Noradrenaline-Specific . Norepinephrine Plasma Membrane Transporter Proteins . Norepinephrine Plasma Membrane Transporters . Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of noradrenergic neurons. They remove NOREPINEPHRINE from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. The norepinephrine transporter regulates signal amplitude and duration at noradrenergic synapses and is the target of ADRENERGIC UPTAKE INHIBITORS. . 0.38
Receptors, Adrenergic. Adrenergic Receptor . Epinephrine Receptors . Norepinephrine Receptors . Receptor, Adrenergic . Adrenergic Receptors . Adrenoceptors . Receptors, Norepinephrine . Receptors, Epinephrine . Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction. . 0.37
