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 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.352 Esterases .
D08.811.277.352.640 Phosphoric Diester Hydrolases .
D08.811.277.352.640.700 Phospholipases .
D08.811.277.352.640.700.700 Type C Phospholipases .
D08.811.277.352.640.700.700.500 Phosphatidylinositol Diacylglycerol-Lyase .
D08.811.399 Isomerases .
D08.811.399.520 Intramolecular Transferases .
D08.811.399.520.750 Phosphotransferases (Phosphomutases) .
D08.811.464 Ligases .
D08.811.464.259 Carbon-Nitrogen Ligases .
D08.811.464.259.400 Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor .
D08.811.464.259.400.300 Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) .
D08.811.520 Lyases .
D08.811.520.650 Phosphorus-Oxygen Lyases .
D08.811.520.650.800 Phosphatidylinositol Diacylglycerol-Lyase .
D08.811.682 Oxidoreductases .
D08.811.682.655 Nitroreductases .
D08.811.682.655.249 GMP Reductase .
D08.811.682.657 Oxidoreductases Acting on Aldehyde or Oxo Group Donors .
D08.811.682.657.350 Ketone Oxidoreductases .
D08.811.682.657.350.760 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) .
D08.811.913 Transferases .
D08.811.913.225 Alkyl and Aryl Transferases .
D08.811.913.225.250 3-Deoxy-7-Phosphoheptulonate Synthase .
D08.811.913.400 Glycosyltransferases .
D08.811.913.400.725 Pentosyltransferases .
D08.811.913.400.725.130 Amidophosphoribosyltransferase .
D08.811.913.400.725.200 ATP Phosphoribosyltransferase .
D08.811.913.400.725.450 Hypoxanthine Phosphoribosyltransferase .
D08.811.913.400.725.700 Orotate Phosphoribosyltransferase .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Hypoxanthine Phosphoribosyltransferase .
HGPRT .
HPRTase .
Hypoxanthine Guanine Phosphoribosyltransferase .
Phosphoribosyltransferase, Guanine .
Phosphoribosyltransferase, Hypoxanthine .
Phosphoribosyltransferase, Hypoxanthine-Guanine .
Pyrophosphorylase, IMP .
Hypoxanthine-Guanine Phosphoribosyltransferase .
IMP Pyrophosphorylase .
Guanine Phosphoribosyltransferase .
HPRT 5454 .
An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or MERCAPTOPURINE to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the LESCH-NYHAN SYNDROME, while partial deficiency results in overproduction of uric acid. EC 2.4.2.8. .
1.00
104330
 
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) .
Carbamoyl-Phosphate Synthase (Glutamine) .
Carbamoylphosphate Synthetase II .
Carbamyl Phosphate Synthase II .
Carbamyl-Phosphate Synthase (Glutamine) .
Synthetase II, Carbamoylphosphate .
Carbamyl Phosphate Synthase (Glutamine) .
An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and glutamine. This enzyme is important in the de novo biosynthesis of pyrimidines. EC 6.3.5.5. .
0.46
0628
 
3-Deoxy-7-Phosphoheptulonate Synthase .
3-Deoxy-Arabino-Heptulosonate-7-Phosphate Synthase .
3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase .
DAH7-P .
2 Dehydro 3 Deoxyphosphoheptonate Aldolase .
3 Deoxy 7 Phosphoheptulonate Synthase .
3 Deoxy Arabino Heptulosonate 7 Phosphate Synthase .
3 Deoxy D Arabino Heptulosonate 7 Phosphate Synthase .
3 Deoxyarabinoheptulosonate 7 Phosphate Synthetase .
Aldolase, 2-Dehydro-3-Deoxyphosphoheptonate .
Aldolase, Phospho-2-Keto-3-Deoxyheptonate .
Phospho 2 Keto 3 Deoxyheptonate Aldolase .
Synthase, 3-Deoxy-7-Phosphoheptulonate .
Synthase, 3-Deoxy-Arabino-Heptulosonate-7-Phosphate .
Synthase, 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate .
Synthase, DAHP .
Synthetase, 3-Deoxyarabinoheptulosonate-7-Phosphate .
2-Dehydro-3-Deoxyphosphoheptonate Aldolase .
3-Deoxyarabinoheptulosonate-7-Phosphate Synthetase .
DAHP Synthase .
Phospho-2-Keto-3-Deoxyheptonate Aldolase .
3-Deoxyarabinoheptulosonate 7-Phosphate Synthetase .
An enzyme that catalyzes the formation of 7-phospho-2-keto-3-deoxy-D-arabinoheptonate from phosphoenolpyruvate and D-erythrose-4-phosphate. It is one of the first enzymes in the biosynthesis of TYROSINE and PHENYLALANINE. This enzyme was formerly listed as EC 4.1.2.15. .
0.45
 
GMP Reductase .
Guanosine 5'-Monophosphate Oxidoreductase .
Guanosine 5'-Monophosphate Reductase .
Guanosine 5'-Phosphate Reductase .
Guanosine Monophosphate Reductase .
Guanylate Reductase .
NADPH:GMP Oxidoreductase (Deaminating) .
NADPH:Guanosine-5'-Phosphate Oxidoreductase (Deaminating) .
5'-Monophosphate Oxidoreductase, Guanosine .
5'-Monophosphate Reductase, Guanosine .
5'-Phosphate Reductase, Guanosine .
Guanosine 5' Monophosphate Oxidoreductase .
Guanosine 5' Monophosphate Reductase .
Guanosine 5' Phosphate Reductase .
Monophosphate Reductase, Guanosine .
Oxidoreductase, Guanosine 5'-Monophosphate .
Reductase, GMP .
Reductase, Guanosine 5'-Monophosphate .
Reductase, Guanosine 5'-Phosphate .
Reductase, Guanosine Monophosphate .
Reductase, Guanylate .
An enzyme that catalyzes the reversible oxidation of inosine 5'-phosphate (IMP) to guanosine 5'-phosphate (GMP) in the presence of AMMONIA and NADP+. This enzyme was formerly classified as EC 1.6.6.8. .
0.44
044
 
Amidophosphoribosyltransferase .
Glutamine-Amidophosphoribosyltransferase .
Phosphoribosyldiphosphate 5-Amidotransferase .
5-Amidotransferase, Phosphoribosyldiphosphate .
Amidotransferase, Phosphoribosyl Pyrophosphate .
Glutamine Amidophosphoribosyltransferase .
Phosphoribosyldiphosphate 5 Amidotransferase .
Pyrophosphate Amidotransferase, Phosphoribosyl .
Glutamine Phosphoribosyl Pyrophosphate Amidotransferase .
Phosphoribosyl Pyrophosphate Amidotransferase .
An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formation of 5-phosphoribosylamine from glutamine and phosphoribosylpyrophosphate. EC 2.4.2.14. .
0.43
0256
 
Orotate Phosphoribosyltransferase .
OMPase .
Orotidine-5'-Monophosphate Phosphohydrolase .
Orotidine 5' Monophosphate Phosphohydrolase .
Orotidine 5' Phosphate Pyrophosphorylase .
Phosphohydrolase, Orotidine-5'-Monophosphate .
Phosphoribosyltransferase, Orotate .
Phosphorylase, Orotidylic Acid .
Pyrophosphorylase, Orotidine-5'-Phosphate .
Orotidine-5'-Phosphate Pyrophosphorylase .
Orotidylic Acid Phosphorylase .
The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10. .
0.42
0550
 
ATP Phosphoribosyltransferase .
Phosphoribosyl ATP Pyrophosphorylase .
Phosphoribosyltransferase, ATP .
Pyrophosphorylase, Phosphoribosyl-ATP .
Phosphoribosyl-ATP Pyrophosphorylase .
An enzyme that catalyzes the first step of the pathway for histidine biosynthesis in Salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield N-1-(5'-phosphoribosyl)-ATP and pyrophosphate. EC 2.4.2.17. .
0.41
173
 
Phosphotransferases (Phosphomutases) .
Phosphomutases .
A group of enzymes that catalyze an intramolecular transfer of a phosphate group. It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. These were previously listed under PHOSPHOTRANSFERASES (EC 2.7.-). (From Enzyme Nomenclature, 1992) EC 5.4.2. .
0.41
1354
 
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) .
2-Oxoisocaproate Dehydrogenase .
Alpha-Keto Acid Dehydrogenase .
BCKA Decarboxylase .
Branched Chain Alpha-Keto Acid Decarboxylase .
Branched Chain Ketoacid Dehydrogenase .
Branched-Chain 2-Oxo Acid Dehydrogenase .
Branched-Chain Keto Acid Dehydrogenase .
Branched-Chain Oxo-Acid Dehydrogenase .
2 Oxoisocaproate Dehydrogenase .
Acid Dehydrogenase, Alpha-Keto .
Alpha Keto Acid Dehydrogenase .
Branched Chain 2 Oxo Acid Dehydrogenase .
Branched Chain Alpha Keto Acid Decarboxylase .
Branched Chain Keto Acid Dehydrogenase .
Branched Chain Oxo Acid Dehydrogenase .
Decarboxylase, BCKA .
Dehydrogenase, 2-Oxoisocaproate .
Dehydrogenase, Alpha-Keto Acid .
Dehydrogenase, Branched-Chain Oxo-Acid .
Oxo-Acid Dehydrogenase, Branched-Chain .
2-Oxoisovalerate Dehydrogenase (Lipoamide) .
A ketone oxidoreductase that catalyzes the overall conversion of alpha-keto acids to ACYL-CoA and CO2. The enzyme requires THIAMINE DIPHOSPHATE as a cofactor. Defects in genes that code for subunits of the enzyme are a cause of MAPLE SYRUP URINE DISEASE. The enzyme was formerly classified as EC 1.2.4.3. .
0.41
0694
 
Phosphatidylinositol Diacylglycerol-Lyase .
Monophosphatidylinositol Phosphodiesterase .
1 Phosphatidylinositol Phosphodiesterase .
Diacylglycerol-Lyase, Phosphatidylinositol .
Phosphatidylinositol Diacylglycerol Lyase .
Phosphodiesterase, 1-Phosphatidylinositol .
Phosphodiesterase, Monophosphatidylinositol .
1-Phosphatidylinositol Phosphodiesterase .
A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction. .
0.40
01403