Deoxyribonuclease (Pyrimidine Dimer). Corrective Endonuclease . Endodeoxyribonuclease (Pyrimidine Dimer) . Endodeoxyribonuclease VIII . Endonuclease V . Endonuclease VIII . Endonuclease, Corrective . An enzyme which catalyzes an endonucleolytic cleavage near PYRIMIDINE DIMERS to produce a 5'-phosphate product. The enzyme acts on the damaged DNA strand, from the 5' side of the damaged site. . 1.00
Deoxyribonuclease IV (Phage T4-Induced). Deoxyriboendonuclease IV . Endonuclease IV . Redoxyendonuclease . An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30. . 0.45
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing). Carbamoyl-Phosphate Synthase (Glutamine) . Carbamoylphosphate Synthetase II . Carbamyl Phosphate Synthase II . Carbamyl-Phosphate Synthase (Glutamine) . Synthetase II, Carbamoylphosphate . Carbamyl Phosphate Synthase (Glutamine) . An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and glutamine. This enzyme is important in the de novo biosynthesis of pyrimidines. EC 6.3.5.5. . 0.38
DNA Damage. Injury, DNA . DNA Damages . DNA Injuries . Damage, DNA . Damages, DNA . Genotoxic Stresses . Injuries, DNA . Stresses, Genotoxic . DNA Injury . Genotoxic Stress . Stress, Genotoxic . Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS. . 0.38
Damage To Production System. Material Damage . Whatever happens to the production of goods or service generation that affects the livelihood systems of a population. (Free translation from the original: Material IV - Glosario de Protección Civil, OPS, 1992) . 0.36