serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.656 Peptide Hydrolases .
D08.811.277.656.262 Cysteine Proteases .
D08.811.277.656.262.500 Cysteine Endopeptidases .
D08.811.277.656.262.500.126 Caspases .
D08.811.277.656.262.500.126.350 Caspases, Effector .
D08.811.277.656.262.500.126.350.700 Caspase 7 .
D08.811.277.656.262.500.126.550 Caspases, Initiator .
D08.811.277.656.262.500.126.550.900 Caspase 9 .
D08.811.277.656.300 Endopeptidases .
D08.811.277.656.300.200 Cysteine Endopeptidases .
D08.811.277.656.300.200.126 Caspases .
D08.811.277.656.300.200.126.350 Caspases, Effector .
D08.811.277.656.300.200.126.350.700 Caspase 7 .
D08.811.277.656.300.200.126.550 Caspases, Initiator .
D08.811.277.656.300.200.126.550.900 Caspase 9 .
D08.811.464 Ligases .
D08.811.464.938 Ubiquitin-Protein Ligase Complexes .
D08.811.464.938.750 Ubiquitin-Protein Ligases .
D08.811.464.938.750.210 Inhibitor of Apoptosis Proteins .
D08.811.464.938.750.210.750 X-Linked Inhibitor of Apoptosis Protein .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.024 Adaptor Proteins, Signal Transducing .
D12.644.360.024.131 CARD Signaling Adaptor Proteins .
D12.644.360.024.131.155 Caspase 9 .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.358 CARD Signaling Adaptor Proteins .
D12.644.360.075.358.155 Caspase 9 .
D12.644.360.075.405 Caspases .
D12.644.360.075.405.350 Caspases, Effector .
D12.644.360.075.405.350.700 Caspase 7 .
D12.644.360.075.405.550 Caspases, Initiator .
D12.644.360.075.405.550.900 Caspase 9 .
D12.644.360.075.437 Inhibitor of Apoptosis Proteins .
D12.644.360.075.437.750 X-Linked Inhibitor of Apoptosis Protein .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.057 Adaptor Proteins, Signal Transducing .
D12.776.157.057.006 CARD Signaling Adaptor Proteins .
D12.776.157.057.006.155 Caspase 9 .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.024 Adaptor Proteins, Signal Transducing .
D12.776.476.024.139 CARD Signaling Adaptor Proteins .
D12.776.476.024.139.155 Caspase 9 .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.358 CARD Signaling Adaptor Proteins .
D12.776.476.075.358.155 Caspase 9 .
D12.776.476.075.405 Caspases .
D12.776.476.075.405.350 Caspases, Effector .
D12.776.476.075.405.350.700 Caspase 7 .
D12.776.476.075.405.550 Caspases, Initiator .
D12.776.476.075.405.550.900 Caspase 9 .
D12.776.476.075.437 Inhibitor of Apoptosis Proteins .
D12.776.476.075.437.750 X-Linked Inhibitor of Apoptosis Protein .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.745 Protease Inhibitors .
D27.505.519.389.745.325 Cysteine Proteinase Inhibitors .
D27.505.519.389.745.325.500 Caspase Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
X-Linked Inhibitor of Apoptosis Protein .
X-Linked IAP Protein .
XIAP Protein .
IAP Protein, X-Linked .
X Linked IAP Protein .
X Linked Inhibitor of Apoptosis Protein .
An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting CASPASE 3; CASPASE 7; and CASPASE 9. .
1.00
31845
 
Caspase Inhibitors .
Capase Activation Inhibitors .
Caspase Activation Blockers .
Caspase Activation Inhibitors .
Caspase Blockers .
Activation Blockers, Caspase .
Activation Inhibitors, Capase .
Activation Inhibitors, Caspase .
Blockers, Caspase .
Blockers, Caspase Activation .
Inhibitors, Capase Activation .
Inhibitors, Caspase .
Inhibitors, Caspase Activation .
Endogenous and exogenous compounds and that either inhibit CASPASES or prevent their activation. .
0.60
25160
 
Caspase 9 .
Apoptotic Protease Activating Factor 3 .
Caspase-9 .
ICE-LAP6 Protein .
ICE-Like Apoptotic Protease 6 .
Pro-Caspase-9 .
Procaspase-9 .
ICE LAP6 Protein .
ICE Like Apoptotic Protease 6 .
Pro Caspase 9 .
Procaspase 9 .
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES. .
0.53
135921
 
Caspase 7 .
Apoptotic Protease Mch-3 .
Caspase-7 .
ICE-Like Apoptotic Protease 3 .
Mch-3 Protease .
Pro-caspase 7 .
Pro-caspase-7 .
Procaspase 7 .
Procaspase-7 .
Apoptotic Protease Mch 3 .
ICE Like Apoptotic Protease 3 .
Mch 3 Protease .
Mch-3, Apoptotic Protease .
Pro caspase 7 .
Protease Mch-3, Apoptotic .
Protease, Mch-3 .
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA. .
0.53
01800
 
Caspases .
A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur. .
0.52
5224289