serw-MX  [xml]  

 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.656 Peptide Hydrolases .
D08.811.277.656.350 Exopeptidases .
D08.811.277.656.350.350 Dipeptidyl-Peptidases and Tripeptidyl-Peptidases .
D08.811.277.656.350.350.687 Peptidyl-Dipeptidase A .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.745 Protease Inhibitors .
D27.505.519.389.745.085 Angiotensin-Converting Enzyme Inhibitors .
 Synonyms & Historicals
Angiotensin-Converting Enzyme Inhibitors .
Angiotensin I-Converting Enzyme Inhibitors .
Angiotensin-Converting Enzyme Antagonists .
Antagonists, Angiotensin-Converting Enzyme .
Antagonists, Kininase II .
Inhibitors, ACE .
Inhibitors, Angiotensin-Converting Enzyme .
Inhibitors, Kininase II .
Kininase II Antagonists .
Angiotensin Converting Enzyme Antagonists .
Angiotensin Converting Enzyme Inhibitors .
Angiotensin I Converting Enzyme Inhibitors .
Antagonists, Angiotensin Converting Enzyme .
Enzyme Antagonists, Angiotensin-Converting .
Enzyme Inhibitors, Angiotensin-Converting .
Inhibitors, Angiotensin Converting Enzyme .
Kininase II Inhibitors .
ACE Inhibitors .
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. .
Peptidyl-Dipeptidase A .
Angiotensin I-Converting Enzyme .
Carboxycathepsin .
Dipeptidyl Peptidase A .
Kininase A .
Angiotensin I Converting Enzyme .
Peptidyl Dipeptidase A .
Angiotensin Converting Enzyme .
Kininase II .
Antigens, CD143 .
CD143 Antigens .
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates. (From Enzyme Nomenclature, 1992) .