serw-MX  [xml]  
 


    
 DeCS Categories

D01 Inorganic Chemicals .
D01.625 Nitrogen Compounds .
D01.625.100 Azides .
D01.625.100.750 Sodium Azide .
D01.857 Sodium Compounds .
D01.857.462 Sodium Azide .
D02 Organic Chemicals .
D02.159 Azides .
D02.172 Azo Compounds .
D02.172.383 Diazonium Compounds .
D02.172.383.383 Diazomethane .
D02.540 Lactones .
D02.540.576 Polyketides .
D02.540.576.500 Macrolides .
D02.540.576.500.992 Erythromycin .
D02.540.576.500.992.050 Azithromycin .
D02.705 Organophosphorus Compounds .
D02.705.672 Phosphoramides .
D02.705.672.875 Thiotepa .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.097 Azirines .
D03.383.097.217 Aziridines .
D03.383.097.217.935 Triethylenephosphoramide .
D03.383.097.217.935.960 Thiotepa .
D03.383.742 Pyrimidines .
D03.383.742.680 Pyrimidine Nucleosides .
D03.383.742.680.705 Thymidine .
D03.383.742.680.705.950 Zidovudine .
D13 Nucleic Acids, Nucleotides, and Nucleosides .
D13.570 Nucleosides .
D13.570.230 Deoxyribonucleosides .
D13.570.230.500 Dideoxynucleosides .
D13.570.230.500.950 Zidovudine .
D13.570.230.855 Thymidine .
D13.570.230.855.950 Zidovudine .
D13.570.685 Pyrimidine Nucleosides .
D13.570.685.705 Thymidine .
D13.570.685.705.950 Zidovudine .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Azirines .
Azacyclopropanes, Unsaturated .
Unsaturated Azacyclopropanes .
Unsaturated azacyclopropane compounds that are three-membered heterocycles of a nitrogen and two carbon atoms. .
1.00
11296
 
Aziridines .
Azacyclopropanes, Saturated .
Dimethyleneimines .
Saturated Azacyclopropanes .
Ethyleneimines .
Azacyclopropanes .
Saturated azacyclopropane compounds. They include compounds with substitutions on CARBON or NITROGEN atoms. .
0.87
22448
 
Azides .
Organic or inorganic compounds that contain the -N3 group. .
0.62
49722
 
Azithromycin .
Azadose .
Azithromycin Dihydrate .
Azithromycin Monohydrate .
Azitrocin .
Azythromycin .
CP-62993 .
Goxal .
Sumamed .
Toraseptol .
Ultreon .
Vinzam .
Zentavion .
Zithromax .
Zitromax .
CP 62993 .
CP62993 .
Dihydrate, Azithromycin .
Monohydrate, Azithromycin .
A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. .
0.53
2274381
 
Diazomethane .
Diazirine .
A diazonium compound with the formula CH2N2. .
0.51
2574
 
Zidovudine .
3'-Azido-2',3'-Dideoxythymidine .
3'-Azido-3'-deoxythymidine .
AZT Antiviral .
AZT, Antiviral .
BW A509U .
BWA-509U .
Retrovir .
3' Azido 2',3' Dideoxythymidine .
3' Azido 3' deoxythymidine .
Antiviral AZT .
BWA 509U .
BWA509U .
Azidothymidine .
AZT (Antiviral) .
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. .
0.49
2259298
 
Sodium Azide .
Azide, Sodium .
NaN3 21302 .
A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed) .
0.47
31807
 
Thiotepa .
AI3-24916 .
Girostan .
NSC-6396 .
Tespa .
Tespamin .
Tris(1-aziridinyl)phosphine Sulfide .
AI3 24916 .
AI324916 .
NSC 6396 .
NSC6396 .
Thio Tepa .
Thiophosphamide .
Thio-Tepa .
Triethylenethiophosphoramide .
A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed). .
0.46
112272