serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.211 Coenzymes .
D08.211.790 Sphingolipid Activator Proteins .
D08.211.790.500 Saposins .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.656 Peptide Hydrolases .
D08.811.277.656.675 Metalloproteases .
D08.811.277.656.675.374 Metalloendopeptidases .
D08.811.277.656.675.374.102 ADAM Proteins .
D09 Carbohydrates .
D09.400 Glycoconjugates .
D09.400.430 Glycoproteins .
D09.400.430.500 ADAM Proteins .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.276 Intercellular Signaling Peptides and Proteins .
D12.644.276.200 CCN Intercellular Signaling Proteins .
D12.644.276.390 Endothelial Growth Factors .
D12.644.276.954 TGF-beta Superfamily Proteins .
D12.644.276.954.200 Bone Morphogenetic Proteins .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.024 Adaptor Proteins, Signal Transducing .
D12.644.360.024.334 Smad Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.057 Adaptor Proteins, Signal Transducing .
D12.776.157.057.170 Smad Proteins .
D12.776.260 DNA-Binding Proteins .
D12.776.260.703 Repressor Proteins .
D12.776.260.713 Smad Proteins .
D12.776.395 Glycoproteins .
D12.776.395.033 ADAM Proteins .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.200 CCN Intercellular Signaling Proteins .
D12.776.467.390 Endothelial Growth Factors .
D12.776.467.942 TGF-beta Superfamily Proteins .
D12.776.467.942.200 Bone Morphogenetic Proteins .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.024 Adaptor Proteins, Signal Transducing .
D12.776.476.024.428 Smad Proteins .
D12.776.624 Neoplasm Proteins .
D12.776.624.776 Tumor Suppressor Proteins .
D12.776.860 Scleroproteins .
D12.776.860.300 Extracellular Matrix Proteins .
D12.776.860.300.200 CCN Intercellular Signaling Proteins .
D12.776.930 Transcription Factors .
D12.776.930.780 Repressor Proteins .
D12.776.930.806 Smad Proteins .
D23 Biological Factors .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.237 CCN Intercellular Signaling Proteins .
D23.529.390 Endothelial Growth Factors .
D23.529.942 TGF-beta Superfamily Proteins .
D23.529.942.200 Bone Morphogenetic Proteins .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Bone Morphogenetic Proteins .
Bone Morphogenetic Protein .
Morphogenetic Protein, Bone .
Morphogenetic Proteins, Bone .
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. .
1.00
9811374
 
TGF-beta Superfamily Proteins .
Transforming Growth Factor beta Superfamily Proteins .
Superfamily Proteins, TGF-beta .
TGF beta Superfamily Proteins .
A large family of cell regulatory proteins which are structurally related to TRANSFORMING GROWTH FACTOR BETA. The superfamily is subdivided into at least three related protein families: BONE MORPHOGENETIC PROTEINS; GROWTH DIFFERENTIATION FACTORS; and TRANSFORMING GROWTH FACTORS. .
0.48
053
 
Smad Proteins .
Mothers Against Decapentaplegic Homolog .
Sma- and Mad-Related Proteins .
A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS. .
0.43
83100
 
ADAM Proteins .
A Disintegrin and Metalloprotease Proteins .
ADAM (A Disintegrin and Metalloprotease) Proteins .
A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain. .
0.40
155596
 
Endothelial Growth Factors .
ECDGF .
Endo-GF .
Endothelial Growth Factor .
Endothelial Growth Factor Polypeptides .
Endothelial Cell Derived Growth Factors .
Growth Factor, Endothelial .
Growth Factor, alpha-Endothelial .
Growth Factor, beta-Endothelial .
Growth Factors, Endothelial .
alpha Endothelial Growth Factor .
beta Endothelial Growth Factor .
alpha-Endothelial Growth Factor .
beta-Endothelial Growth Factor .
Endothelial Cell-Derived Growth Factors .
These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences. .
0.39
338024
 
CCN Intercellular Signaling Proteins .
CCN Family Proteins .
CYR61 CTGF NOV Matricellular Proteins .
Matricellular CCN Proteins .
A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN. .
0.39
0320
 
Repressor Proteins .
Transcriptional Silencing Factors .
Proteins, Repressor .
Silencing Factors, Transcriptional .
Repressor Molecules .
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release. .
0.38
2443329
 
Saposins .
Co-beta-Glucosidase .
Coglucosidase .
Gaucher Activator Protein .
Glucosylceramidase Activator .
SAP-1 Sphingolipid Activator .
SAP-A Protein .
SAP-C Protein .
SAP-D Protein .
Saposin A .
Saposin B .
Saposin C .
Saposin D .
Sphingolipid Activator Protein 1 .
Sphingolipid Activator Protein 2 .
Sphingolipid Activator Protein-1 .
Testibumin .
beta-Glucosidase Activator Protein .
beta-Glucosidase Stimulating Protein .
Co beta Glucosidase .
SAP 1 Sphingolipid Activator .
SAP A Protein .
SAP C Protein .
SAP D Protein .
Sphingolipid Activator, SAP-1 .
beta Glucosidase Activator Protein .
beta Glucosidase Stimulating Protein .
A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin. .
0.38
0623
 
Tumor Suppressor Proteins .
Proteins, Growth Suppressor .
Proteins, Metastasis Suppressor .
Proteins, Tumor Suppressor .
Growth Suppressor Proteins .
Metastasis Suppressor Proteins .
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development. .
0.37
3428431