Sialic Acid Binding Ig-like Lectin 3. Antigens, CD33 . CD33 Antigen . CD33 Antigens . Glycoprotein gp67 . Siglec-3 . Antigen, CD33 . Sialic Acid Binding Ig like Lectin 3 . gp67, Glycoprotein . A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE. . 1.00
ATP Binding Cassette Transporter, Sub-Family G, Member 2. ABCG2 Protein . ABCG2 Transporter . CD338 Antigen . Antigen, CD338 . An ATP binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS. . 0.94
Jagged-1 Protein. Alagille Syndrome Protein . CD339 Antigen . Jagged-1 . Jagged1 Protein . Serrate-1 Protein . Serrate1 Protein . Antigen, CD339 . Jagged 1 . Jagged 1 Protein . Serrate 1 Protein . A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1. . 0.93
