Cytochrome P450 Family 26. CYP26 Cytochrome P450 . CYP26 Enzymes . CYP26 Family . Cytochrome P-450 CYP26 . Cytochrome P 450 CYP26 . Cytochrome P450, CYP26 . A cytochrome P450 enzyme family whose members function in the metabolism of RETINOIC ACID. It includes RETINOIC ACID 4-HYDROXYLASE. . 1.00
Cytochrome P-450 Enzyme System. CYP450 Family . CYP450 Superfamily . Cytochrome P-450 Enzymes . Cytochrome P-450 Families . Cytochrome P-450 Monooxygenase . Cytochrome P-450 Oxygenase . Cytochrome P-450 Superfamily . Cytochrome P450 . Cytochrome P450 Superfamily . Cytochrome p450 Families . P-450 Enzymes . P450 Enzymes . Cytochrome P 450 . Cytochrome P 450 Dependent Monooxygenase . Cytochrome P 450 Enzyme System . Cytochrome P 450 Enzymes . Cytochrome P 450 Families . Cytochrome P 450 Monooxygenase . Cytochrome P 450 Oxygenase . Cytochrome P 450 Superfamily . Enzymes, Cytochrome P-450 . Enzymes, P-450 . Enzymes, P450 . Monooxygenase, Cytochrome P-450 . Monooxygenase, Cytochrome P-450-Dependent . P 450 Enzymes . P-450 Enzymes, Cytochrome . Superfamily, CYP450 . Superfamily, Cytochrome P-450 . Superfamily, Cytochrome P450 . Cytochrome P-450 . Cytochrome P-450-Dependent Monooxygenase . A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. . 0.81
Cytochrome P-450 CYP1B1. Cytochrome P450 CYP1B1 . Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 . Cytochrome P4501B1 . Cytochrome P 450 CYP1B1 . P450 CYP1B1, Cytochrome . A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly. . 0.80
Camphor 5-Monooxygenase. CYP101 . Camphor-5-Monooxygenase . Cytochrome P-450 101 . Cytochrome P-450-cam . Cytochrome P450(cam) . P450cam . Camphor 5 Monooxygenase . Cytochrome P 450 101 . Cytochrome P 450 cam . Cytochrome P-450(cam) . A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidaredoxin, putidaredoxin reductase, and molecular oxygen. This enzyme, encoded by the CAMC gene also known as CYP101, has been crystallized from bacteria and the structure is well defined. Under anaerobic conditions, this enzyme reduces the polyhalogenated compounds bound at the camphor-binding site. . 0.71
