Clostridiales. An order of anaerobic bacteria that are predominantly GRAM POSITIVE within the phylum Firmicutes. It includes the Clostridium and Eubacterium genera. . 1.00
Clostridium. A genus of motile or nonmotile gram-positive bacteria of the family Clostridiaceae. Many species have been identified with some being pathogenic. They occur in water, soil, and in the intestinal tract of humans and lower animals. . 0.79
Clostridiaceae. A non-sulfate spore-forming anaerobic family of Gram-positive bacteria, of the class clostridia. . 0.76
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Tetanus Toxin. Tetanus Toxins . Neurotoxin, Clostridial . Toxin, Clostridium tetani . Toxin, Tetanus . Toxins, Tetanus . Clostridial Neurotoxin . Clostridium tetani Toxin . Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS. . 0.65
Clostridium tetani. The cause of TETANUS in humans and domestic animals. It is a common inhabitant of human and horse intestines as well as soil. Two components make up its potent exotoxin activity, a neurotoxin and a hemolytic toxin. . 0.60
