serw-MX  [xml]  

 DeCS Categories

B03 Bacteria .
B03.300 Endospore-Forming Bacteria .
B03.300.390 Gram-Positive Endospore-Forming Bacteria .
B03.300.390.400 Gram-Positive Endospore-Forming Rods .
B03.300.390.400.200 Clostridium .
B03.300.390.400.200.725 Clostridium tetani .
B03.353 Firmicutes .
B03.353.625 Clostridiales .
B03.353.625.375 Clostridiaceae .
B03.353.625.375.500 Clostridium .
B03.353.625.375.500.725 Clostridium tetani .
B03.510 Gram-Positive Bacteria .
B03.510.415 Gram-Positive Endospore-Forming Bacteria .
B03.510.415.400 Gram-Positive Endospore-Forming Rods .
B03.510.415.400.200 Clostridium .
B03.510.415.400.200.725 Clostridium tetani .
C01 Bacterial Infections and Mycoses .
C01.252 Bacterial Infections .
C01.252.410 Gram-Positive Bacterial Infections .
C01.252.410.222 Clostridium Infections .
C01.252.410.222.864 Tetanus .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.097 Bacterial Proteins .
D12.776.097.872 Tetanus Toxin .
D23 Biological Factors .
D23.946 Toxins, Biological .
D23.946.123 Bacterial Toxins .
D23.946.123.893 Tetanus Toxin .
 Synonyms & Historicals
Tetanus .
Clostridium tetani Infection .
Clostridium tetani Infections .
Infection, Clostridium tetani .
Infections, Clostridium tetani .
A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form. .
Clostridium tetani .
The cause of TETANUS in humans and domestic animals. It is a common inhabitant of human and horse intestines as well as soil. Two components make up its potent exotoxin activity, a neurotoxin and a hemolytic toxin. .
Clostridium Infections .
Clostridium difficile Infection .
Clostridium perfringens Food Poisoning .
Clostridium perfringens Infections .
Clostridium sordellii Infection .
Infections, Clostridium .
Clostridium Infection .
Clostridium difficile Infections .
Clostridium perfringens Infection .
Clostridium sordellii Infections .
Infection, Clostridium .
Infection, Clostridium difficile .
Infection, Clostridium perfringens .
Infection, Clostridium sordellii .
Infections, Clostridium difficile .
Infections, Clostridium perfringens .
Infections, Clostridium sordellii .
Infections with bacteria of the genus CLOSTRIDIUM. .
Tetanus Toxin .
Tetanus Toxins .
Neurotoxin, Clostridial .
Toxin, Clostridium tetani .
Toxin, Tetanus .
Toxins, Tetanus .
Clostridial Neurotoxin .
Clostridium tetani Toxin .
Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS. .