serw-MX  [xml]  
 


    
 DeCS Categories

D01 Inorganic Chemicals .
D01.625 Nitrogen Compounds .
D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.526 Hydrocarbons, Halogenated .
D02.455.526.728 Mustard Compounds .
D02.455.526.728.650 Nitrogen Mustard Compounds .
D02.455.526.728.650.529 Mechlorethamine .
D02.640 Nitro Compounds .
D02.654 Nitroso Compounds .
SP4 Environmental Health .
SP4.011 Science .
SP4.011.097 Chemistry .
SP4.011.097.036 Organic Chemicals .
SP4.011.097.036.644 Nitroso Compounds .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Nitrogen Mustard Compounds .
Compounds, Nitrogen Mustard .
Mustard Compounds, Nitrogen .
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. .
1.00
02859
 
Nitrogen Compounds .
Compounds, Nitrogen .
Inorganic compounds that contain nitrogen as an integral part of the molecule. .
0.82
291218
 
Mechlorethamine .
Bis(2-chloroethyl)methylamine .
Caryolysine .
Cloramin .
Embichin .
Mechlorethamine Hydrochloride .
Mechlorethamine Hydrochloride N-Oxide .
Mechlorethamine N-Oxide .
Methylchlorethamine .
Mitomen .
Mustargen .
NSC-10107 .
NSC-762 .
Nitrogranulogen .
Nitromin .
Hydrochloride N-Oxide, Mechlorethamine .
Hydrochloride, Mechlorethamine .
Mechlorethamine Hydrochloride N Oxide .
Mechlorethamine N Oxide .
N-Oxide, Mechlorethamine Hydrochloride .
N-Oxide, Nitrogen Mustard .
NSC 10107 .
NSC 762 .
NSC10107 .
NSC762 .
Nitrogen Mustard N Oxide .
Chlorethazine .
Chlormethine .
Mechlorethamine Oxide .
Mustine .
Nitrogen Mustard .
Nitrogen Mustard N-Oxide .
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. .
0.81
123102
 
Mustard Compounds .
Compounds, Mustard .
Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents. .
0.75
1556
 
Nitroso Compounds .
Compounds, Nitroso .
Organic compounds containing the nitroso (-N=O) group attached to an organic moiety. .
0.72
104801
 
Nitro Compounds .
Nitrated Compounds .
Compounds having the nitro group, -NO2, attached to carbon. When attached to nitrogen they are nitramines and attached to oxygen they are NITRATES. .
0.71
146580