Cytochrome P450 Family 11. CYP11 Enzymes . CYP11 Family . A cytochrome P450 enzyme family whose members localize to the INNER MITOCHONDRIAL MEMBRANE where they function in the biosynthesis of STEROIDS. . 1.00
0
0
Cytochrome P450 Family 1. CYP1 Enzymes . CYP1 Family . A cytochrome P450 enzyme family whose members function primarily in the metabolism of XENOBIOTICS, including drugs and POLYCYCLIC AROMATIC HYDROCARBONS. . 0.87
Cytochrome P450 Family 17. CYP17 Enzymes . CYP17 Family . A cytochrome P450 enzyme family that functions in the biosynthesis of STEROIDS and includes STEROID 17-ALPHA-HYDROXYLASE. . 0.84
Cytochrome P450 Family 12. CYP12 Enzymes . CYP12 Family . A cytochrome P450 enzyme family that occurs in insects and is expressed in MITOCHONDRIA. . 0.84
Cytochrome P450 Family 19. CYP19 Enzymes . CYP19 Family . A cytochrome P450 enzyme family that includes AROMATASE, which functions in the biosynthesis of ESTROGENS. . 0.83
Cytochrome P-450 Enzyme System. CYP450 Family . CYP450 Superfamily . Cytochrome P-450 Enzymes . Cytochrome P-450 Families . Cytochrome P-450 Monooxygenase . Cytochrome P-450 Oxygenase . Cytochrome P-450 Superfamily . Cytochrome P450 . Cytochrome P450 Superfamily . Cytochrome p450 Families . P-450 Enzymes . P450 Enzymes . Cytochrome P 450 . Cytochrome P 450 Dependent Monooxygenase . Cytochrome P 450 Enzyme System . Cytochrome P 450 Enzymes . Cytochrome P 450 Families . Cytochrome P 450 Monooxygenase . Cytochrome P 450 Oxygenase . Cytochrome P 450 Superfamily . Enzymes, Cytochrome P-450 . Enzymes, P-450 . Enzymes, P450 . Monooxygenase, Cytochrome P-450 . Monooxygenase, Cytochrome P-450-Dependent . P 450 Enzymes . P-450 Enzymes, Cytochrome . Superfamily, CYP450 . Superfamily, Cytochrome P-450 . Superfamily, Cytochrome P450 . Cytochrome P-450 . Cytochrome P-450-Dependent Monooxygenase . A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. . 0.82
Cytochrome P450 Family 2. CYP2 Enzymes . CYP2 Family . A cytochrome P450 enzyme family that includes members which function in the metabolism of STEROIDS; COUMARINS; and NICOTINE. . 0.80
Cytochrome P450 Family 3. CYP3 Enzymes . CYP3 Family . A cytochrome P450 enzyme family that includes members with critical functions in the metabolism of drugs and SEX HORMONES. . 0.79
Cytochrome P450 Family 4. CYP4 Enzymes . CYP4 Family . A cytochrome P450 enzyme family that includes members which function in the metabolism of FATTY ACIDS, especially ARACHIDONIC ACIDS and their derivatives. . 0.78
Cytochrome P450 Family 6. CYP6 Enzymes . CYP6 Family . A cytochrome P450 enzyme family that occurs in insects. Its members function in the metabolism of XENOBIOTICS. . 0.78
