Cytochrome P450 Family 26. CYP26 Cytochrome P450 . CYP26 Enzymes . CYP26 Family . Cytochrome P-450 CYP26 . Cytochrome P 450 CYP26 . Cytochrome P450, CYP26 . A cytochrome P450 enzyme family whose members function in the metabolism of RETINOIC ACID. It includes RETINOIC ACID 4-HYDROXYLASE. . 1.00
Cytochrome P450 Family 2. CYP2 Enzymes . CYP2 Family . A cytochrome P450 enzyme family that includes members which function in the metabolism of STEROIDS; COUMARINS; and NICOTINE. . 0.85
Cytochrome P450 Family 21. CYP21 Enzymes . CYP21 Family . A cytochrome P450 enzyme family that includes STEROID 21-HYDROXYLASE, which functions in the biosynthesis of STEROIDS. . 0.81
Cytochrome P450 Family 27. CYP27 Enzymes . CYP27 Family . A cytochrome P450 enzyme family whose members function in VITAMIN D metabolism and the biosynthesis of BILE ACIDS. . 0.81
Cytochrome P-450 Enzyme System. CYP450 Family . CYP450 Superfamily . Cytochrome P-450 Enzymes . Cytochrome P-450 Families . Cytochrome P-450 Monooxygenase . Cytochrome P-450 Oxygenase . Cytochrome P-450 Superfamily . Cytochrome P450 . Cytochrome P450 Superfamily . Cytochrome p450 Families . P-450 Enzymes . P450 Enzymes . Cytochrome P 450 . Cytochrome P 450 Dependent Monooxygenase . Cytochrome P 450 Enzyme System . Cytochrome P 450 Enzymes . Cytochrome P 450 Families . Cytochrome P 450 Monooxygenase . Cytochrome P 450 Oxygenase . Cytochrome P 450 Superfamily . Enzymes, Cytochrome P-450 . Enzymes, P-450 . Enzymes, P450 . Monooxygenase, Cytochrome P-450 . Monooxygenase, Cytochrome P-450-Dependent . P 450 Enzymes . P-450 Enzymes, Cytochrome . Superfamily, CYP450 . Superfamily, Cytochrome P-450 . Superfamily, Cytochrome P450 . Cytochrome P-450 . Cytochrome P-450-Dependent Monooxygenase . A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. . 0.80
Cytochrome P450 Family 1. CYP1 Enzymes . CYP1 Family . A cytochrome P450 enzyme family whose members function primarily in the metabolism of XENOBIOTICS, including drugs and POLYCYCLIC AROMATIC HYDROCARBONS. . 0.78
Cytochrome P450 Family 3. CYP3 Enzymes . CYP3 Family . A cytochrome P450 enzyme family that includes members with critical functions in the metabolism of drugs and SEX HORMONES. . 0.77
Cytochrome P450 Family 4. CYP4 Enzymes . CYP4 Family . A cytochrome P450 enzyme family that includes members which function in the metabolism of FATTY ACIDS, especially ARACHIDONIC ACIDS and their derivatives. . 0.76
Cytochrome P450 Family 6. CYP6 Enzymes . CYP6 Family . A cytochrome P450 enzyme family that occurs in insects. Its members function in the metabolism of XENOBIOTICS. . 0.76
