serw-MX  [xml]  
 
    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.100 Cytochrome P450 Family 1 .
D08.244.453.491 Cytochrome P450 Family 2 .
D08.244.453.860 Cytochrome P450 Family 3 .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.020 Cytochrome P450 Family 1 .
D08.811.682.690.708.170.450 Cytochrome P450 Family 2 .
D08.811.682.690.708.170.495 Cytochrome P450 Family 3 .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.100 Cytochrome P450 Family 1 .
D12.776.422.220.453.491 Cytochrome P450 Family 2 .
D12.776.422.220.453.860 Cytochrome P450 Family 3 .
 
 Terms
 Synonyms & Historicals		Documents
LILACS e MDL		 
Cytochrome P-450 Enzyme System .
CYP450 Family .
CYP450 Superfamily .
Cytochrome P-450 Enzymes .
Cytochrome P-450 Families .
Cytochrome P-450 Monooxygenase .
Cytochrome P-450 Oxygenase .
Cytochrome P-450 Superfamily .
Cytochrome P450 .
Cytochrome P450 Superfamily .
Cytochrome p450 Families .
P-450 Enzymes .
P450 Enzymes .
Cytochrome P 450 .
Cytochrome P 450 Dependent Monooxygenase .
Cytochrome P 450 Enzyme System .
Cytochrome P 450 Enzymes .
Cytochrome P 450 Families .
Cytochrome P 450 Monooxygenase .
Cytochrome P 450 Oxygenase .
Cytochrome P 450 Superfamily .
Enzymes, Cytochrome P-450 .
Enzymes, P-450 .
Enzymes, P450 .
Monooxygenase, Cytochrome P-450 .
Monooxygenase, Cytochrome P-450-Dependent .
P 450 Enzymes .
P-450 Enzymes, Cytochrome .
Superfamily, CYP450 .
Superfamily, Cytochrome P-450 .
Superfamily, Cytochrome P450 .
Cytochrome P-450 .
Cytochrome P-450-Dependent Monooxygenase .
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. .
1.00
4439776
 
Cytochrome P450 Family 1 .
CYP1 Enzymes .
CYP1 Family .
A cytochrome P450 enzyme family whose members function primarily in the metabolism of XENOBIOTICS, including drugs and POLYCYCLIC AROMATIC HYDROCARBONS. .
0.70
113
 
Cytochrome P450 Family 2 .
CYP2 Enzymes .
CYP2 Family .
A cytochrome P450 enzyme family that includes members which function in the metabolism of STEROIDS; COUMARINS; and NICOTINE. .
0.70
11172
 
Cytochrome P450 Family 3 .
CYP3 Enzymes .
CYP3 Family .
A cytochrome P450 enzyme family that includes members with critical functions in the metabolism of drugs and SEX HORMONES. .
0.69
017