serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.005 Aryl Hydrocarbon Hydroxylases .
D08.244.453.005.500 Cytochrome P-450 CYP1B1 .
D08.244.453.012 Camphor 5-Monooxygenase .
D08.244.453.100 Cytochrome P450 Family 1 .
D08.244.453.100.875 Cytochrome P-450 CYP1B1 .
D08.244.453.491 Cytochrome P450 Family 2 .
D08.244.453.491.250 Cytochrome P-450 CYP2A6 .
D08.244.453.498 Cytochrome P450 Family 26 .
D08.244.453.900 Cytochrome P450 Family 8 .
D08.244.453.900.500 Steroid 12-alpha-Hydroxylase .
D08.244.453.915 Steroid Hydroxylases .
D08.244.453.915.730 Steroid 12-alpha-Hydroxylase .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.010 Aryl Hydrocarbon Hydroxylases .
D08.811.682.690.708.170.010.500 Cytochrome P-450 CYP1B1 .
D08.811.682.690.708.170.012 Camphor 5-Monooxygenase .
D08.811.682.690.708.170.020 Cytochrome P450 Family 1 .
D08.811.682.690.708.170.020.875 Cytochrome P-450 CYP1B1 .
D08.811.682.690.708.170.450 Cytochrome P450 Family 2 .
D08.811.682.690.708.170.450.250 Cytochrome P-450 CYP2A6 .
D08.811.682.690.708.170.485 Cytochrome P450 Family 26 .
D08.811.682.690.708.170.900 Cytochrome P450 Family 8 .
D08.811.682.690.708.170.900.500 Steroid 12-alpha-Hydroxylase .
D08.811.682.690.708.170.915 Steroid Hydroxylases .
D08.811.682.690.708.170.915.730 Steroid 12-alpha-Hydroxylase .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.010 Aryl Hydrocarbon Hydroxylases .
D12.776.422.220.453.010.500 Cytochrome P-450 CYP1B1 .
D12.776.422.220.453.012 Camphor 5-Monooxygenase .
D12.776.422.220.453.100 Cytochrome P450 Family 1 .
D12.776.422.220.453.100.875 Cytochrome P-450 CYP1B1 .
D12.776.422.220.453.491 Cytochrome P450 Family 2 .
D12.776.422.220.453.491.250 Cytochrome P-450 CYP2A6 .
D12.776.422.220.453.498 Cytochrome P450 Family 26 .
D12.776.422.220.453.900 Cytochrome P450 Family 8 .
D12.776.422.220.453.900.500 Steroid 12-alpha-Hydroxylase .
D12.776.422.220.453.915 Steroid Hydroxylases .
D12.776.422.220.453.915.730 Steroid 12-alpha-Hydroxylase .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Cytochrome P450 Family 26 .
CYP26 Cytochrome P450 .
CYP26 Enzymes .
CYP26 Family .
Cytochrome P-450 CYP26 .
Cytochrome P 450 CYP26 .
Cytochrome P450, CYP26 .
A cytochrome P450 enzyme family whose members function in the metabolism of RETINOIC ACID. It includes RETINOIC ACID 4-HYDROXYLASE. .
1.00
020
 
Cytochrome P-450 CYP2A6 .
Coumarin 7-Hydroxylase .
Coumarin Hydroxylase .
Cytochrome P450 CYP2A6 .
Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 .
Coumarin 7 Hydroxylase .
Cytochrome P 450 CYP 2A3 .
Cytochrome P 450 CYP2A6 .
P450 CYP2A6, Cytochrome .
Cytochrome P-450 CYP-2A3 .
A cytochrome P450 enzyme that has specificity for the 7-hydroxylation of coumarin. .
0.89
0918
 
Cytochrome P-450 CYP1B1 .
Cytochrome P450 CYP1B1 .
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 .
Cytochrome P4501B1 .
Cytochrome P 450 CYP1B1 .
P450 CYP1B1, Cytochrome .
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly. .
0.83
01354
 
Steroid 12-alpha-Hydroxylase .
12alpha-Hydroxylase .
CYP8B1 .
Cytochrome P450 8B1 .
Cytochrome P450 CYP8B1 .
Steroid 12-Hydroxylase .
Steroid-12-Hydroxylase .
Steroid-12-Monooxygenase .
Sterol 12 alpha-Hydroxylase .
12 alpha Hydroxylase .
12 alpha-Hydroxylase, Sterol .
12alpha Hydroxylase .
Steroid 12 Hydroxylase .
Steroid 12 Monooxygenase .
Steroid 12 alpha Hydroxylase .
Sterol 12 alpha Hydroxylase .
alpha-Hydroxylase, Sterol 12 .
12-alpha-Hydroxylase .
Steroid 12-Monooxygenase .
Sterol 12-alpha-Hydroxylase .
STEROID 12-HYDROXYLASE .
A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP8B1gene, converts 7-alpha-hydroxy-4-cholesten-3-one to 7-alpha-12-alpha-dihydroxy-4-cholesten-3-one and is required in the synthesis of BILE ACIDS from cholesterol. .
0.82
0114
 
Cytochrome P-450 Enzyme System .
CYP450 Family .
CYP450 Superfamily .
Cytochrome P-450 Enzymes .
Cytochrome P-450 Families .
Cytochrome P-450 Monooxygenase .
Cytochrome P-450 Oxygenase .
Cytochrome P-450 Superfamily .
Cytochrome P450 .
Cytochrome P450 Superfamily .
Cytochrome p450 Families .
P-450 Enzymes .
P450 Enzymes .
Cytochrome P 450 .
Cytochrome P 450 Dependent Monooxygenase .
Cytochrome P 450 Enzyme System .
Cytochrome P 450 Enzymes .
Cytochrome P 450 Families .
Cytochrome P 450 Monooxygenase .
Cytochrome P 450 Oxygenase .
Cytochrome P 450 Superfamily .
Enzymes, Cytochrome P-450 .
Enzymes, P-450 .
Enzymes, P450 .
Monooxygenase, Cytochrome P-450 .
Monooxygenase, Cytochrome P-450-Dependent .
P 450 Enzymes .
P-450 Enzymes, Cytochrome .
Superfamily, CYP450 .
Superfamily, Cytochrome P-450 .
Superfamily, Cytochrome P450 .
Cytochrome P-450 .
Cytochrome P-450-Dependent Monooxygenase .
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. .
0.81
4339776
 
Camphor 5-Monooxygenase .
CYP101 .
Camphor-5-Monooxygenase .
Cytochrome P-450 101 .
Cytochrome P-450-cam .
Cytochrome P450(cam) .
P450cam .
Camphor 5 Monooxygenase .
Cytochrome P 450 101 .
Cytochrome P 450 cam .
Cytochrome P-450(cam) .
A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidaredoxin, putidaredoxin reductase, and molecular oxygen. This enzyme, encoded by the CAMC gene also known as CYP101, has been crystallized from bacteria and the structure is well defined. Under anaerobic conditions, this enzyme reduces the polyhalogenated compounds bound at the camphor-binding site. .
0.74
0429