serw-MX  [xml]  

 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.150 DNA Restriction-Modification Enzymes .
D08.811.150.280 DNA Restriction Enzymes .
D08.811.150.280.260 Deoxyribonucleases, Type II Site-Specific .
D08.811. Deoxyribonuclease EcoRI .
D08.811.277 Hydrolases .
D08.811.277.352 Esterases .
D08.811.277.352.335 Deoxyribonucleases .
D08.811.277.352.335.350 Endodeoxyribonucleases .
D08.811.277.352.335.350.300 DNA Restriction Enzymes .
D08.811.277.352.335.350.300.260 Deoxyribonucleases, Type II Site-Specific .
D08.811.277.352.335.350.300.260.250 Deoxyribonuclease EcoRI .
D08.811.277.352.355 Endonucleases .
D08.811.277.352.355.325 Endodeoxyribonucleases .
D08.811.277.352.355.325.300 DNA Restriction Enzymes .
D08.811.277.352.355.325.300.260 Deoxyribonucleases, Type II Site-Specific .
D08.811.277.352.355.325.300.260.250 Deoxyribonuclease EcoRI .
 Synonyms & Historicals
DNA Restriction-Modification Enzymes .
DNA Restriction Modification Enzymes .
Restriction Modification Systems .
Enzymes, DNA Restriction-Modification .
Modification Systems, Restriction .
Restriction-Modification Enzymes, DNA .
Systems, Restriction Modification .
Systems, Restriction-Modification .
Restriction-Modification Systems .
Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage. .
DNA Restriction Enzymes .
DNA Restriction Enzyme .
Restriction Endonuclease .
Endonuclease, Restriction .
Endonucleases, Restriction .
Enzymes, DNA Restriction .
Restriction Enzyme, DNA .
Restriction Enzymes, DNA .
Restriction Endonucleases .
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1. .
Deoxyribonuclease EcoRI .
Eco RI .
Eco-RI .
EcoRI Endonuclease .
Endodeoxyribonuclease ECoRI .
Endodeoxyribonuclease HsaI .
Endonuclease Eco159I .
Endonuclease Eco82I .
Endonuclease RsrI .
Endonuclease SsoI .
HsaI Endonuclease .
Restriction Endonuclease RsrI .
Deoxyribonuclease SsoI .
DNA Restriction Enzyme EcoRI .
Endonuclease EcoRI .
One of the Type II site-specific deoxyribonucleases (EC It recognizes and cleaves the sequence G/AATTC at the slash. EcoRI is from E coliRY13. Several isoschizomers have been identified. EC 3.1.21.-. .