serw-MX  [xml]  

 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.399 Isomerases .
D08.811.399.403 DNA Topoisomerases .
D08.811.399.403.483 DNA Topoisomerases, Type I .
D08.811.399.403.741 DNA Topoisomerases, Type II .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.687 Poly-ADP-Ribose Binding Proteins .
D12.776.157.687.375 DNA Topoisomerases, Type I .
D12.776.660 Nuclear Proteins .
D12.776.660.720 Poly-ADP-Ribose Binding Proteins .
D12.776.660.720.375 DNA Topoisomerases, Type I .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.892 Topoisomerase Inhibitors .
D27.505.519.389.892.500 Topoisomerase I Inhibitors .
D27.505.954 Therapeutic Uses .
D27.505.954.248 Antineoplastic Agents .
D27.505.954.248.794 Topoisomerase Inhibitors .
D27.505.954.248.794.500 Topoisomerase I Inhibitors .
 Synonyms & Historicals
DNA Topoisomerases, Type I .
DNA Nicking-Closing Proteins .
DNA Relaxing Enzymes .
DNA Type 1 Topoisomerase .
DNA Untwisting Enzymes .
DNA Untwisting Proteins .
Topoisomerase I .
Type I DNA Topoisomerase .
DNA Nicking-Closing Protein .
DNA Relaxing Enzyme .
DNA Relaxing Protein .
DNA Topoisomerase .
DNA Topoisomerase I .
DNA Untwisting Enzyme .
DNA Untwisting Protein .
DNA Untwisting Enzymes .
DNA Topoisomerases, Type I, Eukaryotic .
DNA Topoisomerase I, Eukaryotic .
DNA Topoisomerases, Type I, Bacterial .
DNA Topoisomerase I, Bacterial .
DNA Topoisomerases, Type I, Archaeal .
DNA Untwisting Proteins .
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix. .
Topoisomerase I Inhibitors .
DNA Topoisomerase I Inhibitors .
DNA Type 1 Topoisomerase Inhibitors .
Inhibitors, Topoisomerase 1 .
Inhibitors, Topoisomerase I .
Topoisomerase 1 Inhibitors .
Compounds that inhibit the activity of DNA TOPOISOMERASE I. .
DNA Topoisomerases .
Topoisomerases, DNA .
Enzymes that regulate the topology of DNA by actions such as breaking, relaxing, passing, and rejoining strands of DNA in cells. These enzymes are important components of the DNA replication system. They are classified by their substrate specificities. DNA TOPOISOMERASE I enzymes act on a single strand of DNA. DNA TOPOISOMERASE II enzymes act on double strands of DNA. .
DNA Topoisomerases, Type II .
DNA Topoisomerase II alpha .
DNA Topoisomerase II beta .
DNA Type 2 Topoisomerase .
TOP2A Protein .
TOP2B Protein .
Topoisomerase II .
Topoisomerase II alpha .
Topoisomerase II beta .
Type II DNA Topoisomerase .
alpha, Topoisomerase II .
beta, Topoisomerase II .
DNA Topoisomerase (ATP-Hydrolysing) .
DNA Topoisomerase II .
DNA Topoisomerases, Type II, Eukaryotic .
DNA Topoisomerases, Type II, Bacterial .
DNA Topoisomerase II, Bacterial .
DNA Topoisomerases, Type II, Archaeal .
DNA TOPOISOMERASES that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex. .